ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis (Q42823550)

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scientific article published on 15 October 2007

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English	ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis	scientific article published on 15 October 2007

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scholarly article

1 reference

Europe PubMed Central

8 November 2017

ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis (English)

1 reference

Europe PubMed Central

8 November 2017

0 references

author name string

Hua Fung

1

1 reference

Europe PubMed Central

8 November 2017

Pingfang Liu

2

1 reference

Europe PubMed Central

8 November 2017

Bruce Demple

3

1 reference

Europe PubMed Central

8 November 2017

language of work or name

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publication date

15 October 2007

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Europe PubMed Central

8 November 2017

Molecular and Cellular Biology

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Europe PubMed Central

8 November 2017

27

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Europe PubMed Central

8 November 2017

24

1 reference

Europe PubMed Central

8 November 2017

8834-8847

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Europe PubMed Central

8 November 2017

DNA repair protein involved in heart and blood development

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As(III) transcriptionally activates the gadd45a gene via the formation of H2O2

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Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA.

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Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA

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Molecular and biological roles of Ape1 protein in mammalian base excision repair

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Two essential but distinct functions of the mammalian abasic endonuclease

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The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism

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Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene

1 reference

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27 May 2018

All roads lead to ATF4

1 reference

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Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

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Effect of arsenic on transcription factor AP-1 and NF-kappaB DNA binding activity and related gene expression

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United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia

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Key role of a downstream specificity protein 1 site in cell cycle-regulated transcription of the AP endonuclease gene APE1/APEX in NIH3T3 cells

1 reference

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Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells

1 reference

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Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation

1 reference

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Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites

1 reference

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Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.

1 reference

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Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity

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Recent advances in the protocols of transgenic mouse mutation assays.

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27 May 2018

Going APE over ref-1.

1 reference

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An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

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A method for detecting abasic sites in living cells: age-dependent changes in base excision repair

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Presence of activating transcription factor 4 (ATF4) in the porcine anterior pituitary

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Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres.

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Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation.

1 reference

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1 reference

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Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals

1 reference

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Comparison of the promoters of the mouse (APEX) and human (APE) apurinic endonuclease genes

1 reference

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Asbestos increases mammalian AP-endonuclease gene expression, protein levels, and enzyme activity in mesothelial cells

1 reference

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1 reference

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Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells

1 reference

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Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

1 reference

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The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

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Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation

1 reference

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Programmed cell death and mutation induction in AHH-1 human lymphoblastoid cells exposed to m-amsa

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Intracellular localization of the Apn1 DNA repair enzyme of Saccharomyces cerevisiae. Nuclear transport signals and biological role.

1 reference

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Incision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNA

1 reference

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Characterization of the promoter region of the human apurinic endonuclease gene (APE).

1 reference

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Mutagenesis by apurinic/apyrimidinic sites

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Low dose exposure to sodium arsenite synergistically interacts with UV radiation to induce mutations and alter DNA repair in human cells

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1 reference

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10.1128/MCB.00974-07

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https://api.fatcat.wiki/v0/release/3mjfj75wsfh23odjqcramf76xe

30 July 2022

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