MAPK mediates RAS-induced chromosome instability (Q42807220)

7 November 2017

MAPK mediates RAS-induced chromosome instability (English)

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7 November 2017

Saavedra HI

1

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7 November 2017

Fukasawa K

series ordinal

2

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7 November 2017

Conn CW

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3

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7 November 2017

Stambrook PJ

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4

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7 November 2017

language of work or name

English

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publication date

1 December 1999

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Journal of Biological Chemistry

7 November 2017

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7 November 2017

274

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7 November 2017

53

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7 November 2017

38083-38090

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Proteins regulating Ras and its relatives

7 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Isolation of a transforming sequence from a human bladder carcinoma cell line

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Sequential protein kinase reactions controlling cell growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Raf meets Ras: completing the framework of a signal transduction pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

p120 GAP modulates Ras activation of Jun kinases and transformation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

A role for endothelial NO synthase in LTP revealed by adenovirus-mediated inhibition and rescue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Expression of Rap 1 suppresses genomic instability of H-ras transformed mouse fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Involvement offos in spontaneous and ultraviolet light-induced genetic changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Mitotic and post mitotic consequences of genomic instability induced by oncogenic Ha-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

H-ras expression, genetic instability, and acquisition of metastatic ability by rat prostatic cancer cells following v-H-ras oncogene transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Kinetochore immunofluorescence in micronuclei: a rapid method for the in situ detection of aneuploidy and chromosome breakage in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Mos overexpression in Swiss 3T3 cells induces meiotic-like alterations of the mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Ras signalling and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Selective activation of oncogenic Ha-ras-induced apoptosis in NIH/3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Differential regulation of discrete apoptotic pathways by Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Analysis of micronuclei induced by 2-chlorobenzylidene malonitrile (CS) using fluorescence in situ hybridization with telomeric and centromeric DNA probes, and flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

De novo formation of several features of a centromere following introduction of a Y alphoid YAC into mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Cell cycle tyrosine phosphorylation of p34cdc2 and a microtubule-associated protein kinase homolog in Xenopus oocytes and eggs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Initiation of Xenopus oocyte maturation by activation of the mitogen-activated protein kinase cascade.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Induction of Xenopus oocyte meiotic maturation by MAP kinase.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

What does Mos do in oocytes and somatic cells?

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

A role for mitogen-activated protein kinase in the spindle assembly checkpoint in XTC cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Requirement for MAPK activation for normal mitotic progression in Xenopus egg extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Activation of the MKK/ERK pathway during somatic cell mitosis: direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Casein kinase II catalyzes a mitotic phosphorylation on threonine 1342 of human DNA topoisomerase IIalpha, which is recognized by the 3F3/2 phosphoepitope antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

21 January 2018

The spindle checkpoint

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https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Cytogenetic findings in 111 ovarian cancer patients: therapy-related chromosome aberrations and heterochromatic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Differentiation of micronuclei in mouse bone marrow cells: a comparison between CREST staining and fluorescent in situ hybridization with centromeric and telomeric DNA probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

The identification of micronucleated chromosomes: a possible assay for aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Application of antikinetochore antibody staining (CREST staining) to micronuclei in erythrocytes induced in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Immunofluorescent staining of kinetochores in micronuclei: a new assay for the detection of aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Kinetochore identification in micronuclei in mouse bone-marrow erythrocytes: an assay for the detection of aneuploidy-inducing agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Classification of micronuclei in murine erythrocytes: immunofluorescent staining using CREST antibodies compared to in situ hybridization with biotinylated gamma satellite DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Baseline and phosphoramide mustard-induced sister-chromatid exchanges in pharmacists handling anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

Kinetochores and the checkpoint mechanism that monitors for defects in the chromosome segregation machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.38083

21 January 2018

Identifiers

DOI

10.1074/JBC.274.53.38083

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7 November 2017

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