The cytoprotective aminothiol WR1065 activates p53 through a non-genotoxic signaling pathway involving c-Jun N-terminal kinase. (Q42806263)

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16 December 2019

title

The cytoprotective aminothiol WR1065 activates p53 through a non-genotoxic signaling pathway involving c-Jun N-terminal kinase (English)

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16 December 2019

5

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16 December 2019

Pierre Hainaut

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16 December 2019

author name string

Olivier Pluquet

1

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16 December 2019

Sophie North

2

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16 December 2019

Anindita Bhoumik

3

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16 December 2019

Konstantinos Dimas

4

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16 December 2019

language of work or name

English

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publication date

16 January 2003

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Journal of Biological Chemistry

16 December 2019

published in

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16 December 2019

volume

278

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16 December 2019

issue

14

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16 December 2019

page(s)

11879-11887

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Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer

16 December 2019

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Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines

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Restoration of wild-type conformation and activity of a temperature-sensitive mutant of p53 (p53(V272M)) by the cytoprotective aminothiol WR1065 in the esophageal cancer cell line TE-1.

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M207396200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12531896%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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