Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation (Q42795900)

7 November 2017

Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation (English)

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7 November 2017

R E Silvany

1

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7 November 2017

S Eliazer

series ordinal

2

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7 November 2017

N C Wolff

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3

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7 November 2017

R L Ilaria

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4

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7 November 2017

language of work or name

English

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publication date

1 September 2000

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7 November 2017

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7 November 2017

19

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7 November 2017

39

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7 November 2017

4523-4530

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203811

7 November 2017

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cites work

EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Molecular biology of the Ewing's sarcoma/primitive neuroectodermal tumor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Insulin-like growth factor-I-mediated neurite outgrowth in vitro requires mitogen-activated protein kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

In situ visualization of intratumor growth factor signaling: immunohistochemical localization of activated ERK/MAP kinase in glial neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Hyperexpression of mitogen-activated protein kinase in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

7 January 2021

Fusion of an ETS-family gene, EIAF, to EWS by t(17;22)(q12;q12) chromosome translocation in an undifferentiated sarcoma of infancy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

7 January 2021

Molecular phylogeny of the ETS gene family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

7 January 2021

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203811

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203811

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Dimensions Publication ID

7 November 2017

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1 reference