Overexpression of Dyrk1A causes the defects in synaptic vesicle endocytosis (Q42785129)

7 November 2017

Overexpression of Dyrk1A causes the defects in synaptic vesicle endocytosis (English)

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7 November 2017

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Yoonju Kim

1

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7 November 2017

Joohyun Park

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2

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7 November 2017

Woo-Joo Song

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3

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7 November 2017

Sunghoe Chang

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4

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7 November 2017

3 December 2010

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7 November 2017

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7 November 2017

18

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7 November 2017

3

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7 November 2017

164-172

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Down syndrome phenotypes: the consequences of chromosomal imbalance

7 November 2017

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Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

21 January 2018

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DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects.

21 January 2018

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Microdeletion of the Down syndrome critical region at 21q22.

21 January 2018

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DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly

21 January 2018

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Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

21 January 2018

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Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome

21 January 2018

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Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate

21 January 2018

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MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins

21 January 2018

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Dyrk1A binds to multiple endocytic proteins required for formation of clathrin-coated vesicles

21 January 2018

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Assignment of SYNJ1 to human chromosome 21q22.2 and Synj12 to the murine homologous region on chromosome 16C3-4 by in situ hybridization

21 January 2018

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Excessive expression of synaptojanin in brains with Down syndrome.

21 January 2018

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Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome

21 January 2018

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Role of phosphorylation in regulation of the assembly of endocytic coat complexes

21 January 2018

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The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis

21 January 2018

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Glutamate regulates actin-based motility in axonal filopodia

21 January 2018

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Mnb/Dyrk1A phosphorylation regulates the interaction of dynamin 1 with SH3 domain-containing proteins

21 January 2018

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SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis

21 January 2018

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Focusing on clathrin-mediated endocytosis

21 January 2018

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Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages

21 January 2018

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Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling

21 January 2018

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Chromosome 21 and down syndrome: from genomics to pathophysiology

21 January 2018

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Kinetic properties of a MNB/DYRK1A mutant suitable for the elucidation of biochemical pathways

21 January 2018

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Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation

21 January 2018

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Down syndrome and mouse models.

21 January 2018

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A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

21 January 2018

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Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

21 January 2018

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Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.

21 January 2018

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Activity-dependent control of bulk endocytosis by protein dephosphorylation in central nerve terminals

21 January 2018

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The phospho-dependent dynamin-syndapin interaction triggers activity-dependent bulk endocytosis of synaptic vesicles

21 January 2018

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Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

21 January 2018

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Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.

21 January 2018

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Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene

21 January 2018

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ERK1/2 is an endogenous negative regulator of the gamma-secretase activity

21 January 2018

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The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals

21 January 2018

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DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

21 January 2018

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Protein phosphorylation is required for endocytosis in nerve terminals: potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000321994

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7 November 2017

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