Non-erythropoietic erythropoietin derivatives protect from light-induced and genetic photoreceptor degeneration. (Q42729265)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Non-erythropoietic erythropoietin derivatives protect from light-induced and genetic photoreceptor degeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

main subject

photoreceptor protein

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Enrico M. Surace

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Alberto Auricchio

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Carolina Iodice

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Umberto Di Vicino

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Ida Annunziata

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

19 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

2251-2262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait

26 January 2020

cites work

1 reference

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Erythropoietic stimulating agents

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The Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cells

27 May 2018

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Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutations

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27 May 2018

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27 May 2018

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Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin

27 May 2018

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27 May 2018

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27 May 2018

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Neuroprotective gene therapy for the treatment of inherited retinal degeneration.

27 May 2018

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Rodent electroretinography: methods for extraction and interpretation of rod and cone responses

27 May 2018

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Constitutive and AP20187-induced Ret activation in photoreceptors does not protect from light-induced damage

27 May 2018

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COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas

27 May 2018

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Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling

27 May 2018

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Programmed cell death in retinal degeneration: targeting apoptosis in photoreceptors as potential therapy for retinal degeneration

27 May 2018

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27 May 2018

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AAV-mediated gene transfer for retinal diseases

27 May 2018

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Neuroprotective effects of erythropoietin in the rat hippocampus after pilocarpine-induced status epilepticus

27 May 2018

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27 May 2018

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Hypoxic preconditioning and erythropoietin protect retinal neurons from degeneration

27 May 2018

1 reference

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A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells

27 May 2018

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The brain erythropoietin system and its potential for therapeutic exploitation in brain disease

27 May 2018

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GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells

27 May 2018

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Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration

27 May 2018

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Emerging biological roles for erythropoietin in the nervous system

27 May 2018

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Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration

27 May 2018

1 reference

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Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor

27 May 2018

1 reference

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Leber congenital amaurosis linked to AIPL1: a mouse model reveals destabilization of cGMP phosphodiesterase

27 May 2018

1 reference

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Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration

27 May 2018

1 reference

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Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice

27 May 2018

1 reference

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Functional cross-talk between cytokine receptors revealed by activating mutations in the extracellular domain of the beta-subunit of the GM-CSF receptor

27 May 2018

1 reference

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Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size.

27 May 2018

1 reference

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HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

27 May 2018

1 reference

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Retinal degeneration mutants in the mouse

27 May 2018

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Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

27 May 2018

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A single-step affinity column for purification of serotype-5 based adeno-associated viral vectors.

27 May 2018

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Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column.

27 May 2018

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Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo

27 May 2018

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Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury

27 May 2018

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High throughput production, screening and analysis of adeno-associated viral vectors

27 May 2018

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Structure of adeno-associated virus vector DNA following transduction of the skeletal muscle

27 May 2018

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Efficiency of signalling through cytokine receptors depends critically on receptor orientation

27 May 2018

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In vivo evidence that erythropoietin protects neurons from ischemic damage

27 May 2018

1 reference

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The beta chain of the interleukin-3 receptor functionally associates with the erythropoietin receptor.

27 May 2018

1 reference

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Structure, function, and activation of the erythropoietin receptor

27 May 2018

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Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice

27 May 2018

1 reference

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Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells

27 May 2018

1 reference

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27 May 2018

The future of r-HuEPO.

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Erythropoietin induces tyrosine phosphorylation of the beta chain of the GM-CSF receptor

27 May 2018

1 reference

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Structural role of amino acids 99-110 in recombinant human erythropoietin

27 May 2018

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Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light

27 May 2018

1 reference

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Systemic gene delivery protects the photoreceptors in the retinal degeneration slow mouse.

27 May 2018

1 reference

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Developmental profile of erythropoietin and its receptor in guinea-pig retina

16 August 2018

1 reference

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Local erythropoietin signaling enhances regeneration in peripheral axons.

16 August 2018

1 reference

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Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes

16 August 2018

1 reference

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Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation.

16 August 2018

1 reference

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Erythropoietin is both neuroprotective and neuroregenerative following optic nerve transection.

16 August 2018

1 reference

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Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice.

16 August 2018

1 reference

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Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors

16 August 2018

1 reference

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High expression level of recombinant human erythropoietin in the milk of non-transgenic goats.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Intravitreal administration of erythropoietin and preservation of retinal ganglion cells in an experimental rat model of glaucoma

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Retinal degeneration in Aipl1-deficient mice: a new genetic model of Leber congenital amaurosis

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration

16 August 2018

1 reference

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Derivatives of erythropoietin that are tissue protective but not erythropoietic.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

The decision to prematurely terminate a trial of R-HuEPO due to thrombotic events.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Effect of erythropoietin axotomy-induced apoptosis in rat retinal ganglion cells

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Erythropoietin and erythropoietin receptor in human ischemic/hypoxic brain.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Protection of mouse photoreceptors by survival factors in retinal degenerations.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Erythropoietin structure-function relationships: high degree of sequence homology among mammals.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090200

Efficacy of tribromoethanol anesthesia in mice.

16 August 2018

1 reference

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Neurotrophic factors cause activation of intracellular signaling pathways in Müller cells and other cells of the inner retina, but not photoreceptors

16 August 2018

1 reference

12 December 2020

Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans

1 reference

12 December 2020

Functional and structural role of arginine 103 in human erythropoietin

1 reference

12 December 2020

Mapping of the active site of recombinant human erythropoietin

1 reference

12 December 2020

Identification of a neurotrophic sequence in erythropoietin

1 reference

12 December 2020

Erythropoietin is neuroprotective in models of HIV sensory neuropathy

1 reference

12 December 2020

High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)

1 reference

12 December 2020

Absence of receptor outer segments in the retina of rds mutant mice

1 reference

12 December 2020

Development and degeneration of retina in rds mutant mice: the electroretinogram

1 reference

12 December 2020

β Common receptor integrates the erythropoietin signaling in activation of endothelial nitric oxide synthase

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDR115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21421996%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference