The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix (Q42728931)

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25 January 2020

title

The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix (English)

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25 January 2020

0 references

9

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25 January 2020

Keisuke Horiuchi

13

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25 January 2020

author name string

Takahide Tohmonda

1

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25 January 2020

Yoshiteru Miyauchi

2

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25 January 2020

Rajarshi Ghosh

3

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25 January 2020

Masaki Yoda

4

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25 January 2020

Shinichi Uchikawa

5

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25 January 2020

Jiro Takito

6

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25 January 2020

Hideo Morioka

7

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25 January 2020

Masaya Nakamura

8

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25 January 2020

Kazuhiro Chiba

10

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25 January 2020

Yoshiaki Toyama

11

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25 January 2020

Fumihiko Urano

12

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publication date

18 March 2011

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25 January 2020

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25 January 2020

volume

12

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25 January 2020

issue

5

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25 January 2020

page(s)

451-457

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Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation

25 January 2020

cites work

1 reference

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Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome

27 May 2018

1 reference

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Transcriptional control of skeletogenesis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

Signal integration in the endoplasmic reticulum unfolded protein response

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

Autophagy is activated for cell survival after endoplasmic reticulum stress

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

Regulation of osteoblast differentiation by transcription factors

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

Endoplasmic reticulum stress: cell life and death decisions.

27 May 2018

1 reference

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A trip to the ER: coping with stress

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

An essential role in liver development for transcription factor XBP-1

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

Regulation of ER molecular chaperone prevents bone loss in a murine model for osteoporosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090012

A transgenic mouse model for monitoring endoplasmic reticulum stress

16 August 2018

1 reference

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16 August 2018

Identifiers

DOI

10.1038/EMBOR.2011.34

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25 January 2020

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25 January 2020

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