Microbial Demethylation of Immunosuppressant FK-506: Isolation of 31-O-FK-506-Specific Demethylase Showing Cytochrome P-450 Characteristics from Streptomyces rimosus MA187. (Q42701596)

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scientific article published on October 1995

Language	Label	Description	Also known as
English	Microbial Demethylation of Immunosuppressant FK-506: Isolation of 31-O-FK-506-Specific Demethylase Showing Cytochrome P-450 Characteristics from Streptomyces rimosus MA187.	scientific article published on October 1995

Statements

scholarly article

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17 January 2020

Microbial Demethylation of Immunosuppressant FK-506: Isolation of 31-O-FK-506-Specific Demethylase Showing Cytochrome P-450 Characteristics from Streptomyces rimosus MA187 (English)

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17 January 2020

immunosuppression

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inferred from title

Streptomyces rimosus

object named as

Streptomyces rimosus

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inferred from title

author name string

Shafiee A

1

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17 January 2020

Chen T

2

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17 January 2020

Cameron P

3

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1 October 1995

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17 January 2020

Applied and Environmental Microbiology

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17 January 2020

61

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17 January 2020

10

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17 January 2020

3544-3548

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27 May 2018

Enzymology of FK-506 biosynthesis. Purification and characterization of 31-O-desmethylFK-506 O:methyltransferase from Streptomyces sp. MA6858.

1 reference

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Isoenzyme-specific phosphorylation of cytochromes P-450 and other drug metabolizing enzymes

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FK 506 for liver, kidney, and pancreas transplantation

1 reference

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In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism

1 reference

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Cytochrome b5 reduction by NADPH-cytochrome P-450 reductase

1 reference

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Microbial transformation of immunosuppressive compounds. I. Desmethylation of FK506 and immunomycin (FR 900520) by Actinoplanes sp. ATCC 53771

1 reference

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12 December 2020

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Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

1 reference

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Macrolide antibiotic biosynthesis: isolation and properties of two forms of 6-deoxyerythronolide B hydroxylase from Saccharopolyspora erythraea (Streptomyces erythreus)

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Recent advances in the use of enzyme-catalysed reactions in organic synthesis

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Evidence for the participation of cytochrome b 5 in hepatic microsomal mixed-function oxidation reactions

1 reference

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Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone

1 reference

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FK 506 metabolism in human liver microsomes: investigation of the involvement of cytochrome P450 isozymes other than CYP3A4

1 reference

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Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins)

1 reference

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Identifiers

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17 January 2020

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17 January 2020

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