Dendritic cell-targeted vaccines--hope or hype? (Q42696952)

5 November 2017

Dendritic cell-targeted vaccines--hope or hype? (English)

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5 November 2017

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Wolfgang Kastenmüller

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1

object named as

Wolfgang Kastenmüller

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5 November 2017

Kathrin Kastenmüller

2

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PubMed ID

25190285

5 November 2017

Christian Kurts

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3

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PubMed ID

25190285

5 November 2017

Robert A Seder

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4

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5 November 2017

5 September 2014

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Nature Reviews Immunology

5 November 2017

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5 November 2017

14

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5 November 2017

705-711

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5 November 2017

10

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Vaccines: correlates of vaccine-induced immunity

5 November 2017

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Advancing Toward HIV-1 Vaccine Efficacy through the Intersections of Immune Correlates

31 March 2020

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Protective immunity against malaria after vaccination

31 March 2020

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Tuberculosis vaccines--rethinking the current paradigm

31 March 2020

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Antigen presentation and T cell stimulation by dendritic cells

31 March 2020

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The use of dendritic cells in cancer immunotherapy

31 March 2020

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Cancer immunotherapy via dendritic cells

31 March 2020

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Dendritic cells loaded with killed allogeneic melanoma cells can induce objective clinical responses and MART-1 specific CD8+ T-cell immunity

31 March 2020

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Third generation dendritic cell vaccines for tumor immunotherapy

31 March 2020

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Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally Circulating DC Subsets.

31 March 2020

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Toll-dependent selection of microbial antigens for presentation by dendritic cells

31 March 2020

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Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

31 March 2020

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CD8 T cell responses to infectious pathogens.

31 March 2020

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New horizons in adjuvants for vaccine development

31 March 2020

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Vaccine adjuvants: putting innate immunity to work

31 March 2020

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Immunostimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism

31 March 2020

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Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity

31 March 2020

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Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity

31 March 2020

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Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses.

31 March 2020

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Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.

31 March 2020

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HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

31 March 2020

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Adjuvant-free IgG responses induced with antigen coupled to antibodies against class II MHC.

31 March 2020

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Class II-targeted antigen is superior to CD40-targeted antigen at stimulating humoral responses in vivo

31 March 2020

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Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates

31 March 2020

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Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

31 March 2020

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The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells

31 March 2020

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Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens.

31 March 2020

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Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells

31 March 2020

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Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

31 March 2020

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Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A.

31 March 2020

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Delivery of the HIV-1 Tat protein to dendritic cells by the CyaA vector induces specific Th1 responses and high affinity neutralizing antibodies in non human primates.

31 March 2020

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Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis

31 March 2020

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Taking dendritic cells into medicine

31 March 2020

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Cutting edge: langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo

31 March 2020

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Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

31 March 2020

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Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype.

31 March 2020

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CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses

31 March 2020

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Circulating specific antibodies enhance systemic cross-priming by delivery of complexed antigen to dendritic cells in vivo

31 March 2020

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Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells

31 March 2020

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Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation

31 March 2020

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Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells

31 March 2020

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Immature human dendritic cells express asialoglycoprotein receptor isoforms for efficient receptor-mediated endocytosis

31 March 2020

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Targeting dendritic cells--why bother?

31 March 2020

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Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.

31 March 2020

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Cross-presentation by human dendritic cell subsets

31 March 2020

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Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types

31 March 2020

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Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

31 March 2020

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Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

31 March 2020

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Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation.

31 March 2020

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Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

31 March 2020

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

31 March 2020

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

31 March 2020

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Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function in inflamed tissues

31 March 2020

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Vascular normalization in Rgs5-deficient tumours promotes immune destruction

31 March 2020

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The blockade of immune checkpoints in cancer immunotherapy

31 March 2020

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Cutting edge: Toll-like receptor 9 expression is not required for CpG DNA-aided cross-presentation of DNA-conjugated antigens but essential for cross-priming of CD8 T cells

31 March 2020

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Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites

31 March 2020

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Protective CD8 T cell immunity triggered by CpG-protein conjugates competes with the efficacy of live vaccines

31 March 2020

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Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cell-mediated immunity.

31 March 2020

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Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity

31 March 2020

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A Toll-like receptor-2-directed fusion protein vaccine against tuberculosis

31 March 2020

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A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses

31 March 2020

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DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells

31 March 2020

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Targeting Uptake Receptors on Human Plasmacytoid Dendritic Cells Triggers Antigen Cross-Presentation and Robust Type I IFN Secretion

31 March 2020

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Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation

31 March 2020

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Induction of protective immunity against Mycobacterium tuberculosis by delivery of ESX antigens into airway dendritic cells.

31 March 2020

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Ligation of CD11c during vaccination promotes germinal centre induction and robust humoral responses without adjuvant.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25190285

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Specialized role of migratory dendritic cells in peripheral tolerance induction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25190285

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Targeted antigen presentation using crosslinked antibody heteroaggregates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25190285

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI3727

1 reference

5 November 2017

1 reference

PubMed ID

25190285