Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation. (Q42659880)

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18 March 2020

title

Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation (English)

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Lars Klareskog

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Jimmy Ytterberg

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Vijay Joshua

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Nataliya K Tarasova

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Dorothea Rutishauser

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Roman Zubarev

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Anca I Catrina

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Johan Grunewald

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Anders Eklund

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Johan Rönnelid

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18 March 2020

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Aase Haj Hensvold

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Per Johan Jakobsson

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Vivianne Malmström

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Gudrun Reynisdottir

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author name string

Elena Ossipova

6

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C Magnus Sköld

9

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18 March 2020

language of work or name

English

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publication date

9 May 2014

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Annals of the Rheumatic Diseases

18 March 2020

published in

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volume

74

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issue

9

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page(s)

1772-1777

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Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis

18 March 2020

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Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors

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Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

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Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis

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A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination

21 January 2018

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Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

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Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity?

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Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis

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The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin

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Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin

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Citrullinated fibrinogen detected as a soluble citrullinated autoantigen in rheumatoid arthritis synovial fluids

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Deiminated Epstein-Barr virus nuclear antigen 1 is a target of anti-citrullinated protein antibodies in rheumatoid arthritis

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Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis

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Citrullination is an inflammation-dependent process

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Detection, evaluation and minimization of nonenzymatic deamidation in proteomic sample preparation

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Structural changes and antibody enrichment in the lungs are early features of anti-citrullinated protein antibody-positive rheumatoid arthritis.

21 January 2018

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Chemosensory proteins, major salivary factors in caterpillar mandibular glands.

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In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling

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Opposing effects of HLA-DRB1*13 alleles on the risk of developing anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis

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Targeted analysis of protein citrullination using chemical modification and tandem mass spectrometry

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Modification of citrulline residues with 2,3-butanedione facilitates their detection by liquid chromatography/mass spectrometry

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A technique for the specific enrichment of citrulline-containing peptides

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Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis

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Fine specificity of anti-citrullinated peptide antibodies discloses a heterogeneous antibody population in rheumatoid arthritis

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