Astrocytic tight junctions control inflammatory CNS lesion pathogenesis (Q42644144)

4 November 2017

Astrocytic tight junctions control inflammatory CNS lesion pathogenesis (English)

1 reference

4 November 2017

10

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6 June 2020

Candice Chapouly

14

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6 June 2020

author name string

Sam Horng

1

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6 June 2020

Anthony Therattil

2

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6 June 2020

Sarah Moyon

3

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6 June 2020

Alexandra Gordon

4

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6 June 2020

Karla Kim

5

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6 June 2020

Azeb Tadesse Argaw

6

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6 June 2020

Yuko Hara

7

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6 June 2020

John N Mariani

8

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6 June 2020

Setsu Sawai

9

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6 June 2020

Edward D Crandall

11

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6 June 2020

Michael V Sofroniew

13

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6 June 2020

Gareth R John

15

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6 June 2020

Zea Borok

12

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6 June 2020

language of work or name

English

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publication date

24 July 2017

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Journal of Clinical Investigation

4 November 2017

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6 June 2020

volume

127

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6 June 2020

issue

8

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6 June 2020

page(s)

3136-3151

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describes a project that uses

6 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5531407/fullTextXML

inferred from PubMed Central ID database lookup

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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Interleukin-1β and interleukin-1 receptor antagonist appear in grey matter additionally to white matter lesions during experimental multiple sclerosis

27 May 2018

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27 May 2018

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Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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The innate immune system in demyelinating disease

27 May 2018

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Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

27 May 2018

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Synaptic distributions of GluA2 and PKMζ in the monkey dentate gyrus and their relationships with aging and memory

27 May 2018

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Claudin-1 expression in airway smooth muscle exacerbates airway remodeling in asthmatic subjects

27 May 2018

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Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging

27 May 2018

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Berberine attenuates experimental autoimmune encephalomyelitis in C57 BL/6 mice

27 May 2018

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27 May 2018

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Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage

27 May 2018

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IL-11 regulates autoimmune demyelination

27 May 2018

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Structural determinants of Junctional Adhesion Molecule A (JAM-A) function and mechanisms of intracellular signaling

27 May 2018

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Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

27 May 2018

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VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown

27 May 2018

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LFA-1 binding destabilizes the JAM-A homophilic interaction during leukocyte transmigration

27 May 2018

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Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis.

27 May 2018

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Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

27 May 2018

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Fibrinogen inhibits neurite outgrowth via beta 3 integrin-mediated phosphorylation of the EGF receptor

27 May 2018

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The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease

27 May 2018

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IL-1beta regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program.

27 May 2018

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27 May 2018

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A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

27 May 2018

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Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

27 May 2018

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IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel

27 May 2018

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Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice

27 May 2018

1 reference

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Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium

27 May 2018

1 reference

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Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms

27 May 2018

1 reference

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Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice

27 May 2018

1 reference

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The structure and function of claudins, cell adhesion molecules at tight junctions.

27 May 2018

1 reference

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Claudins regulate the intestinal barrier in response to immune mediators

27 May 2018

1 reference

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Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis

27 May 2018

1 reference

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Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions.

27 May 2018

1 reference

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Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

27 May 2018

1 reference

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Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathology.

27 May 2018

1 reference

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Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis

27 May 2018

1 reference

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Protective effect of transforming growth factor beta 1 on experimental autoimmune diseases in mice

27 May 2018

1 reference

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A randomized, controlled trial of corticosteroids in the treatment of acute optic neuritis. The Optic Neuritis Study Group

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

High dose steroids in acute relapses of multiple sclerosis: MRI evidence for a possible mechanism of therapeutic effect

27 May 2018

1 reference

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Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

Focal MMP-2 and MMP-9 activity at the blood-brain barrier promotes chemokine-induced leukocyte migration.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

Interleukin-1 beta is required for the early evolution of reactive astrogliosis following CNS lesion.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brain.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

Methyl-β-Cyclodextrin Increases Permeability of Caco-2 Cell Monolayers by Displacing Specific Claudins from Cholesterol Rich Domains Associated with Tight Junctions

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5531407

A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease

1 December 2018

1 reference

12 December 2020

Reciprocal regulation of the junctional proteins claudin-1 and connexin43 by interleukin-1beta in primary human fetal astrocytes

1 reference

12 December 2020

Demyelinating events in rheumatoid arthritis after drug exposures

1 reference

12 December 2020

Expression of type II nitric oxide synthase in primary human astrocytes and microglia: role of IL-1beta and IL-1 receptor antagonist

1 reference

12 December 2020

The adhesion molecule and cytokine profile of multiple sclerosis lesions

1 reference

12 December 2020

Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration

1 reference

12 December 2020

Production of IL-1beta and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI91301

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28737509%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28737509%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference