The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors. (Q42638343)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9463378%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors (English)

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9 November 2019

5

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9 November 2019

author name string

R S Lo

1

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9 November 2019

Y G Chen

2

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9 November 2019

Y Shi

3

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9 November 2019

N P Pavletich

4

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9 November 2019

language of work or name

English

0 references

publication date

1 February 1998

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9 November 2019

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9 November 2019

volume

17

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9 November 2019

issue

4

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9 November 2019

page(s)

996-1005

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TGF-beta signalling through the Smad pathway

9 November 2019

cites work

1 reference

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Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

27 May 2018

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Signaling through scaffold, anchoring, and adaptor proteins

27 May 2018

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

27 May 2018

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Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase

27 May 2018

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

27 May 2018

1 reference

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Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

27 May 2018

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Smad4 and FAST-1 in the assembly of activin-responsive factor

27 May 2018

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Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium

27 May 2018

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Mechanism of TGFbeta receptor inhibition by FKBP12

27 May 2018

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Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

27 May 2018

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27 May 2018

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A structural basis for mutational inactivation of the tumour suppressor Smad4

27 May 2018

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

27 May 2018

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Cloning and characterization of a novel member of the human Mad gene family (MADH6)

27 May 2018

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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

27 May 2018

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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

27 May 2018

1 reference

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The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

27 May 2018

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Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway

27 May 2018

1 reference

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

27 May 2018

1 reference

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Intracellular signalling: the mad way to do it.

27 May 2018

1 reference

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Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

27 May 2018

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Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth

27 May 2018

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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

27 May 2018

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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

27 May 2018

1 reference

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TGFbeta signaling: receptors, transducers, and Mad proteins.

27 May 2018

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27 May 2018

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A human Mad protein acting as a BMP-regulated transcriptional activator

27 May 2018

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Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

27 May 2018

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

27 May 2018

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Transcriptional regulation by extracellular signals: mechanisms and specificity

27 May 2018

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Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster

27 May 2018

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Transforming growth factor-beta inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor

27 May 2018

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Daughters against dpp modulates dpp organizing activity in Drosophila wing development

27 May 2018

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Smad6 inhibits signalling by the TGF-beta superfamily.

16 August 2018

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Mothers against dpp participates in a DDP/TGF-beta responsive serine-threonine kinase signal transduction cascade.

16 August 2018

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16 August 2018

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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

16 August 2018

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Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170449

Mad acts downstream of Dpp receptors, revealing a differential requirement for dpp signaling in initiation and propagation of morphogenesis in the Drosophila eye.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170449

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170449

Identification of receptors for type-beta transforming growth factor

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9463378

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/EMBOJ/17.4.996

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9463378%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9463378%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference