Integrin expression and function in the response of primary culture hepatic stellate cells to connective tissue growth factor (CCN2). (Q42632299)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406330%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Integrin expression and function in the response of primary culture hepatic stellate cells to connective tissue growth factor (CCN2) (English)

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31 January 2020

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1

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31 January 2020

author name string

David R Brigstock

series ordinal

2

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31 January 2020

publication date

19 April 2010

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Journal of Cellular and Molecular Medicine

31 January 2020

published in

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31 January 2020

volume

15

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31 January 2020

issue

5

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31 January 2020

page(s)

1087-1095

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Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes

31 January 2020

cites work

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Connective tissue growth factor: context-dependent functions and mechanisms of regulation

27 May 2018

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Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo

27 May 2018

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Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to connective tissue growth factor/CCN2 because of an increase in the levels of endogenous fibronectin.

27 May 2018

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Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells

27 May 2018

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Functions and mechanisms of action of CCN matricellular proteins

27 May 2018

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Defining therapeutic targets for liver fibrosis: exploiting the biology of inflammation and repair

27 May 2018

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RNA interfering connective tissue growth factor prevents rat hepatic stellate cell activation and extracellular matrix production

27 May 2018

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27 May 2018

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Disruption of connective tissue growth factor by short hairpin RNA inhibits collagen synthesis and extracellular matrix secretion in hepatic stellate cells

27 May 2018

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27 May 2018

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Connective tissue growth factor with a novel fibronectin binding site promotes cell adhesion and migration during rat oval cell activation

27 May 2018

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Intrinsic biological activity of the thrombospondin structural homology repeat in connective tissue growth factor

27 May 2018

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CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1

27 May 2018

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A novel integrin alpha5beta1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cells

27 May 2018

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Activation of nuclear factor kappa B (NF-kappaB) by connective tissue growth factor (CCN2) is involved in sustaining the survival of primary rat hepatic stellate cells

27 May 2018

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CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin

27 May 2018

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Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan

27 May 2018

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Initial signaling of the fibronectin receptor (alpha5beta1 integrin) in hepatic stellate cells is independent of tyrosine phosphorylation

27 May 2018

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Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis

27 May 2018

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CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cells

27 May 2018

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Establishment of a recombinant expression system for connective tissue growth factor (CTGF) that models CTGF processing in utero

27 May 2018

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The heparin-binding 10 kDa fragment of connective tissue growth factor (CTGF) containing module 4 alone stimulates cell adhesion

27 May 2018

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Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions

27 May 2018

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Activation of hepatic stellate cells--a key issue in liver fibrosis

27 May 2018

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The CCN family of angiogenic regulators: the integrin connection

27 May 2018

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Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10,000 forms of connective tissue growth factor.

27 May 2018

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siRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats.

27 May 2018

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Connective tissue growth factor (CCN2) in rat pancreatic stellate cell function: integrin alpha5beta1 as a novel CCN2 receptor

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16 August 2018

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Connective tissue growth factor induces c-fos gene activation and cell proliferation through p44/42 MAP kinase in primary rat hepatic stellate cells

16 August 2018

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Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells

16 August 2018

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Down-regulation of connective tissue growth factor and type I collagen mRNA expression by connective tissue growth factor antisense oligonucleotide during experimental liver fibrosis

16 August 2018

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Effects and regulation of connective tissue growth factor on hepatic stellate cells.

16 August 2018

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Expression of the integrin alpha8beta1 during pulmonary and hepatic fibrosis

16 August 2018

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Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells.

16 August 2018

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Stellate cells: a moving target in hepatic fibrogenesis

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differences in regulation of type I collagen synthesis in primary and passaged hepatic stellate cell cultures: the role of alpha5beta1-integrin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of fibronectin receptor, integrin alpha 5 beta 1 of hepatic stellate cells in rat liver fibrosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1582-4934.2010.01072.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406330%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406330%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference