The effects of compounds varying in selectivity as 5-HT(1A) receptor antagonists in three rat models of anxiety (Q42629405)

4 November 2017

The effects of compounds varying in selectivity as 5-HT(1A) receptor antagonists in three rat models of anxiety (English)

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4 November 2017

1

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4 November 2017

Rodgers RJ

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PubMed ID

10884565

4 November 2017

Perrault G

series ordinal

3

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PubMed ID

10884565

4 November 2017

Sanger DJ

series ordinal

4

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4 November 2017

1 July 2000

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4 November 2017

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4 November 2017

39

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4 November 2017

1848-1857

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4 November 2017

10

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Buspirone: future directions

4 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

(-)-pindolol and (+/-)-tertatolol affect rat hippocampal 5-HT levels through mechanisms involving not only 5-HT1A, but also 5-HT1B receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Effects of pindobind 5-hydroxytryptamine1A (5-HT1A), a novel and potent 5-HT1A antagonist, on social and agonistic behaviour in male albino mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Comparison of different behavioral test situations used in psychopharmacology for measurement of anxiety.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Link between emotional memory and anxiety states: a study by principal component analysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Attenuation of CCK-induced aversion in rats on the elevated x-maze by the selective 5-HT1A receptor antagonists (+) WAY100135 and WAY100635.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Direct evidence for an important species difference in the mechanism of 8-OH-DPAT-induced hypothermia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Serotonin, but not dopamine, metabolites are increased in selected brain regions of subordinate male rats in a colony environment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Anxiolytic-like profile of p-MPPI, a novel 5HT1A receptor antagonist, in the murine elevated plus-maze.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Influence of 5-HT1A receptor antagonism on plus-maze behaviour in mice. I. Pindolol enantiomers and pindobind 5-HT1A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Influence of 5-HT1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN-190.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Comparative effects of novel 5-HT1A receptor ligands, LY293284, LY315712 and LY297996, on plus-maze anxiety in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Tolerance to acute anxiolysis but no withdrawal anxiogenesis in mice treated chronically with 5-HT1A receptor antagonist, WAY 100635.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

An ethological analysis of the effects of chlordiazepoxide and bretazenil (Ro 16-6028) in the murine elevated plus-maze

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

On the elevated plus-maze the anxiolytic-like effects of the 5-HT(1A) agonist, 8-OH-DPAT, but not the anxiogenic-like effects of the 5-HT(1A) partial agonist, buspirone, are blocked by the 5-HT1A antagonist, WAY 100635.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Isolation rearing of rats alters release of 5-hydroxytryptamine and dopamine in the frontal cortex: an in vivo electrochemical study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Novel environment and cat odor change GABA and 5-HT release and uptake in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Comparative study of pre- and postsynaptic 5-HT1A receptor modulation of anxiety in two ethological animal tests.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Buspirone. A preliminary review of its pharmacological properties and therapeutic efficacy as an anxiolytic

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Risk assessment behaviour: evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus-maze test.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Characterization of the behavioral profile of the non-peptide CRF receptor antagonist CP-154,526 in anxiety models in rodents. Comparison with diazepam and buspirone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Behavioural profiles in the mouse defence test battery suggest anxiolytic potential of 5-HT(1A) receptor antagonists.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

The use of the rat elevated plus-maze to discriminate between non-selective and BZ-1 (omega 1) selective, benzodiazepine receptor ligands.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

A review of the validity and variability of the elevated plus-maze as an animal model of anxiety

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

The effects of 5-HT1A receptor agonists, 5-HT1A receptor antagonists and their interaction on the fear-potentiated startle response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Psychological stress increases serotonin release in the rat amygdala and prefrontal cortex assessed by in vivo microdialysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Effects of 5-HT1A receptor ligands in a modified Geller-Seifter conflict model in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

A potential 5-HT1A receptor antagonist: p-MPPI.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Characterization of a novel and potent 5-hydroxytryptamine1A receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

The use of a plus-maze to measure anxiety in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Serotonin and pain: evidence that activation of 5-HT1A receptors does not elicit antinociception against noxious thermal, mechanical and chemical stimuli in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Ultrasonic vocalizations in rat pups: effects of serotonergic ligands

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Increased anxiety of mice lacking the serotonin1A receptor

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Serotonin receptor 1A knockout: an animal model of anxiety-related disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Somatodendritic 5-HT1A receptors are critically involved in the anxiolytic effects of 8-OH-DPAT

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Animal models of ??anxiety??: where next?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Antianxiety and behavioral suppressant actions of the novel 5-HT1A receptor agonist, flesinoxan

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Profile of action of 5-HT3 receptor antagonists, ondansetron and WAY 100289, in the elevated plus-maze test of anxiety of mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

The role of 5-HT receptor subtypes in the anxiolytic effects of selective serotonin reuptake inhibitors in the rat ultrasonic vocalization test

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Ethopharmacological analysis of 5-HT ligands on the rat elevated plus-maze.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Fear-potentiated startle elevates catecholamine levels in the dorsomedial hypothalamus of rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Behavioural and pharmacological characterisation of the elevated "zero-maze" as an animal model of anxiety.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

The yohimbine-induced anticonflict effect in the rat, Part I. Involvement of noradrenergic, serotonergic and endozepinergic(?) mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

The yohimbine-induced anticonflict effect in the rat, Part II. Neurochemical findings

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Effects of 5-HT1A receptor agonists, partial agonists and a silent antagonist on the performance of the conditioned emotional response test in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

A simple and reliable conflict procedure for testing anti-anxiety agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Effect of repeated ipsapirone treatment on hippocampal excitatory synaptic transmission in the freely behaving rat: role of 5-HT1A receptors and relationship to anxiolytic effect.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Effects of conditioned fear stress on 5-HT release in the rat prefrontal cortex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

Synthesis and evaluation of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p- iodobenzamido]ethyl]piperazine (p-MPPI): a new iodinated 5-HT1A ligand.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2800%2900074-5

10.1016/S0028-3908(00)00074-5

7 January 2021

Identifiers

DOI

1 reference

4 November 2017

1 reference

PubMed ID

10884565