Thrombin related peptide TP508 promoted fracture repair in a mouse high energy fracture model (Q42610559)

3 November 2017

Thrombin related peptide TP508 promoted fracture repair in a mouse high energy fracture model (English)

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3 November 2017

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Brain M Hanratty

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3 November 2017

James T Ryaby

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3 November 2017

Xiao-Hua Pan

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3

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3 November 2017

Gang Li

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4

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3 November 2017

29 January 2009

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Journal of Orthopaedic Surgery and Research

3 November 2017

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3 November 2017

4

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3 November 2017

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https://scigraph.springernature.com/pub.10.1186/1749-799x-4-1

3 November 2017

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cites work

Thrombin peptide, TP508, stimulates angiogenic responses in animal models of dermal wound healing, in chick chorioallantoic membranes, and in cultured human aortic and microvascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Effects of thrombin peptides on wound healing and proliferation and migration of normal human epidermal keratinocyte (NHEK)

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Local injection of thrombin-related peptide (TP508) in PPF/PLGA microparticles-enhanced bone formation during distraction osteogenesis.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

The non-proteolytically active thrombin peptide TP508 stimulates angiogenic sprouting

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

rhBMP-2, rhVEGF(165), rhPTN and thrombin-related peptide, TP508 induce chemotaxis of human osteoblasts and microvascular endothelial cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Time for treating bone fracture using rhBMP-2: a randomised placebo controlled mouse fracture trial.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Bone formation is enhanced by thrombin-related peptide TP508 during distraction osteogenesis.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Thrombin peptide (TP508) treatment of rat growth plate cartilage cells promotes proliferation and retention of the chondrocytic phenotype while blocking terminal endochondral differentiation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Production of consistent crush lesions in murine quadriceps muscle--a biomechanical, histomorphological and immunohistochemical study.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Repair of rabbit segmental defects with the thrombin peptide, TP508.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

A reliable externally fixated murine femoral fracture model that accounts for variation in movement between animals.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Acceleration of full-thickness wound healing in normal rats by the synthetic thrombin peptide, TP508.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649908

Thrombin peptide TP508 accelerates closure of dermal excisions in animal tissue with surgically induced ischemia

16 August 2018

1 reference

12 December 2020

Prevention of fracture healing in rats by an inhibitor of angiogenesis

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12 December 2020

The thrombin peptide, TP508, enhances cytokine release and activates signaling events

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12 December 2020

Thrombin peptide (TP508) promotes fracture repair by up-regulating inflammatory mediators, early growth factors, and increasing angiogenesis

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12 December 2020

Identifiers

DOI

10.1186/1749-799X-4-1

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Dimensions Publication ID

3 November 2017

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3 November 2017

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