Elucidating human phosphatase-substrate networks (Q42599269)

3 November 2017

Elucidating human phosphatase-substrate networks (English)

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3 November 2017

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3 November 2017

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3 November 2017

Maja Köhn

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author name string

Xun Li

series ordinal

1

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3 November 2017

14 May 2013

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3 November 2017

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3 November 2017

6

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3 November 2017

275

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3 November 2017

rs10

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Signaling--2000 and beyond

3 November 2017

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Protein tyrosine phosphatases: from genes, to function, to disease

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Protein tyrosine phosphatases in the human genome

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Serine/threonine phosphatases: mechanism through structure

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

From promiscuity to precision: protein phosphatases get a makeover

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Human HAD phosphatases: structure, mechanism, and roles in health and disease

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

UniProt Knowledgebase: a hub of integrated protein data

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Evolution of protein phosphatases in plants and animals

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Determinants for Dephosphorylation of the RNA Polymerase II C-Terminal Domain by Scp1

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

The human phosphatase interactome: An intricate family portrait

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

HuPho: the human phosphatase portal

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Phosphoinositide phosphatases in a network of signalling reactions

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Interconversion of the kinetic identities of the tandem catalytic domains of receptor-like protein-tyrosine phosphatase PTPalpha by two point mutations is synergistic and substrate-dependent.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Molecular mechanisms of the PRL phosphatases

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Myotubularin phosphatases: policing 3-phosphoinositides

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

The metastasis-promoting phosphatase PRL-3 shows activity toward phosphoinositides

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Human Protein Reference Database--2009 update

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

PSICQUIC and PSISCORE: accessing and scoring molecular interactions

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

LocDB: experimental annotations of localization for Homo sapiens and Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

PhosphoPOINT: a comprehensive human kinase interactome and phospho-protein database.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

A gene atlas of the mouse and human protein-encoding transcriptomes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Novel Ser/Thr protein phosphatase 5 (PP5) regulated targets during DNA damage identified by proteomics analysis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Challenges and opportunities in the development of protein phosphatase-directed therapeutics.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

InterPro: the integrative protein signature database

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Calcineurin dephosphorylates glycogen synthase kinase-3 beta at serine-9 in neuroblast-derived cells

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Phospho.ELM: a database of phosphorylation sites--update 2008.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

A quantitative model for cyclin-dependent kinase control of the cell cycle: revisited

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Cdc14: a highly conserved family of phosphatases with non-conserved functions?

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Systematic Discovery of In Vivo Phosphorylation Networks

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

KEGG for integration and interpretation of large-scale molecular data sets

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

PID: the Pathway Interaction Database

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Basic local alignment search tool

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Tyrosine phosphorylation of c-ErbB-2 is regulated by the cellular form of prostatic acid phosphatase in human prostate cancer cells

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

FYVE-DSP2, a FYVE domain-containing dual specificity protein phosphatase that dephosphorylates phosphotidylinositol 3-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

MTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Endogenous viruses: insights into viral evolution and impact on host biology

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTP

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Isolation and characterization of a novel dual specific phosphatase, HVH2, which selectively dephosphorylates the mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Human Cdc14A reverses CDK1 phosphorylation of Cdc25A on serines 115 and 320.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Human Cdc14A phosphatase modulates the G2/M transition through Cdc25A and Cdc25B.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Identification of PP1alpha as a caspase-9 regulator in IL-2 deprivation-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Gene ontology: tool for the unification of biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

The Pfam protein families database

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

The protein-phosphatome of the human malaria parasite Plasmodium falciparum

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

SMART 7: recent updates to the protein domain annotation resource

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

PROSITE, a protein domain database for functional characterization and annotation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

EMBOSS: the European Molecular Biology Open Software Suite

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

21 January 2018

The Protein Data Bank

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Cytoscape 2.8: new features for data integration and network visualization

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

WebLogo: A Sequence Logo Generator

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

Dephosphorylation of distinct sites on microtubule-associated protein MAP1B by protein phosphatases 1, 2A and 2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003203

10.1126/SCISIGNAL.2003203

21 January 2018

Identifiers

DOI

1 reference

3 November 2017

1 reference

PubMed ID

23674824