Differential effects of p63 mutants on transactivation of p53 and/or p63 responsive genes. (Q42581268)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18626511%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Differential effects of p63 mutants on transactivation of p53 and/or p63 responsive genes (English)

1 reference

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10 January 2020

author

Ramakrishna Kommagani

series ordinal

2

1 reference

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10 January 2020

author name string

Shama K Khokhar

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18626511%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Madhavi P Kadakia

series ordinal

3

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10 January 2020

publication date

1 October 2008

1 reference

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10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18626511%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

18

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10 January 2020

issue

10

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10 January 2020

page(s)

1061-1073

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https://scigraph.springernature.com/pub.10.1038/cr.2008.82

10 January 2020

exact match

0 references

cites work

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TAp63gamma-induced apoptosis mediated by apoptosis inducing factor in human esophageal squamous carcinoma EC9706 cells

28 May 2018

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Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?

28 May 2018

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p63 overexpression induces the expression of Sonic Hedgehog.

28 May 2018

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p51/p63, a novel p53 homologue, potentiates p53 activity and is a human cancer gene therapy candidate

28 May 2018

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Glyoxalase II, a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73, is a pro-survival factor of the p53 family

28 May 2018

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p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.

28 May 2018

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GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner

28 May 2018

1 reference

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The unique NH2-terminally deleted (DeltaN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the DeltaN variant of p63.

28 May 2018

1 reference

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The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells

28 May 2018

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Differential recognition of response elements determines target gene specificity for p53 and p63

28 May 2018

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TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

28 May 2018

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TAp63gamma can substitute for p53 in inducing expression of the maspin tumor suppressor.

28 May 2018

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The expression of TA and DeltaNp63 are regulated by different mechanisms in liver cells.

28 May 2018

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Maspin expression is transactivated by p63 and is critical for the modulation of lung cancer progression

28 May 2018

1 reference

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Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder.

28 May 2018

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

28 May 2018

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Delta Np63 alpha expression is regulated by the phosphoinositide 3-kinase pathway.

28 May 2018

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DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development

28 May 2018

1 reference

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Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains

28 May 2018

1 reference

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Loss of p63 expression is associated with tumor progression in bladder cancer

28 May 2018

1 reference

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p63 expression in normal, hyperplastic and malignant breast tissues

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

The p53 family member genes are involved in the Notch signal pathway

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

P63 and P73: P53 mimics, menaces and more

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

Split-hand/split-foot malformation is caused by mutations in the p63 gene on 3q27.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

28 May 2018

1 reference

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The transcriptional activities of p53 and its homologue p51/p63: similarities and differences.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

p63 is a p53 homologue required for limb and epidermal morphogenesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

28 May 2018

1 reference

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Cloning and functional analysis of human p51, which structurally and functionally resembles p53

28 May 2018

1 reference

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

28 May 2018

1 reference

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Identification of vitamin D receptor as a target of p63.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

TAp63gamma (p51A) and dNp63alpha (p73L), two major isoforms of the p63 gene, exert opposite effects on the vascular endothelial growth factor (VEGF) gene expression.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

Regulation of p63 function by Mdm2 and MdmX.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760224

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

16 August 2018

2 references

Crossref

https://api.crossref.org/works/10.1038%2FCR.2008.82

21 January 2018

12 December 2020

p51A (TAp63gamma), a p53 homolog, accumulates in response to DNA damage for cell regulation

1 reference

12 December 2020

Frequent alteration of p63 expression in human primary bladder carcinomas

1 reference

12 December 2020

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

1 reference

12 December 2020

Pattern of p63 mutations and their phenotypes--update

1 reference

12 December 2020

Further phenotypic and genetic variation in ADULT syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1038/CR.2008.82

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18626511%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18626511%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference