Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase (Q42541962)

2 November 2017

Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase (English)

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inositol phosphoceramide synthase activity

2 November 2017

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Gene Ontology release 2020-05-02

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Mandala SM

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2 November 2017

Thornton RA

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2 November 2017

Milligan J

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2 November 2017

Rosenbach M

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2 November 2017

Garcia-Calvo M

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2 November 2017

Bull HG

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2 November 2017

Harris G

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2 November 2017

Abruzzo GK

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2 November 2017

Flattery AM

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2 November 2017

Gill CJ

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2 November 2017

Bartizal K

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2 November 2017

Dreikorn S

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2 November 2017

Kurtz MB

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2 November 2017

language of work or name

English

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publication date

1 June 1998

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Journal of Biological Chemistry

2 November 2017

8

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based on heuristic

inferred from page(s)

published in

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2 November 2017

273

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2 November 2017

24

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2 November 2017

14942-14949

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The future of antifungal therapy

2 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.273.24.14942

Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin

21 January 2018

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Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14942

ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.24.14942

Unusual effect of myo-inositol on phospholipid biosynthesis in Cryptococcus neoformans

21 January 2018

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Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.24.14942

Elevated recombination rates in transcriptionally active DNA

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.24.14942

Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5

21 January 2018

1 reference

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Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

21 January 2018

1 reference

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The yeast gene ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle-sparking sterol

21 January 2018

1 reference

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Yeast multidrug resistance: the PDR network.

21 January 2018

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Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells

21 January 2018

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Functions of ceramide in coordinating cellular responses to stress

21 January 2018

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Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology

21 January 2018

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Stress-induced apoptosis and the sphingomyelin pathway

21 January 2018

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Sphingolipid metabolites: members of a new class of lipid second messengers

21 January 2018

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A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae

21 January 2018

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Essential role for diacylglycerol in protein transport from the yeast Golgi complex.

21 January 2018

1 reference

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Biosynthesis of mannosylinositolphosphoceramide in Saccharomyces cerevisiae is dependent on genes controlling the flow of secretory vesicles from the endoplasmic reticulum to the Golgi

21 January 2018

1 reference

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Organelle structure, function, and inheritance in yeast: a role for fatty acid synthesis?

21 January 2018

1 reference

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Cloning and characterization of the plasma membrane H(+)-ATPase from Candida albicans

21 January 2018

1 reference

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Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

21 January 2018

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Accumulation of glucosylceramides in multidrug-resistant cancer cells

21 January 2018

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Inhibition of serine palmitoyl-transferase activity by lipoxamycin

21 January 2018

1 reference

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The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporormiella australis. Producing organism, fermentation, isolation, and biological activity

21 January 2018

1 reference

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Galbonolides A and B--two non-glycosidic antifungal macrolides

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Rustmicin, a new macrolide antibiotic active against wheat stem rust fungus

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Identifiers

DOI

10.1074/JBC.273.24.14942

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2 November 2017

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