Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA). (Q42539213)

2 November 2017

Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA). (English)

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2 November 2017

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Shih C

1

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2 November 2017

Habeck LL

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2 November 2017

Mendelsohn LG

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2 November 2017

Chen VJ

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2 November 2017

Schultz RM

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2 November 2017

1 January 1998

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Advances in Enzyme Regulation

2 November 2017

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2 November 2017

38

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2 November 2017

135-152

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Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin

2 November 2017

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7 January 2021

Phase II trials of trimetrexate in advanced adult soft tissue sarcoma. Studies of the Canadian Sarcoma Group and the National Cancer Institute of Canada Clinical Trials Group

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https://api.crossref.org/works/10.1016%2FS0065-2571%2897%2900017-4

7 January 2021

Quinazoline antifolate thymidylate synthase inhibitors: heterocyclic benzoyl ring modifications

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https://api.crossref.org/works/10.1016%2FS0065-2571%2897%2900017-4

7 January 2021

A dideazatetrahydrofolate analogue lacking a chiral center at C-6, N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]-L-glutamic acid, is an inhibitor of thymidylate synthase

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7 January 2021

Quinazoline antifolates inhibiting thymidylate synthase: synthesis of four oligo(L-gamma-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid and their enzyme inhibition

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7 January 2021

Mammalian folyl polyglutamate synthetase: partial purification and properties of the mouse liver enzyme

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7 January 2021

Mammalian folylpoly-gamma-glutamate synthetase. 1. Purification and general properties of the hog liver enzyme

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7 January 2021

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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7 January 2021

Evaluation of ascorbic acid in protecting labile folic acid derivatives

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7 January 2021

A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleoside triphosphates in cell extracts

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7 January 2021

Mammalian folylpoly-gamma-glutamate synthetase. 4. In vitro and in vivo metabolism of folates and analogues and regulation of folate homeostasis

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7 January 2021

The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. Cloning, sequencing, expression, purification, kinetic analysis, and domain mapping

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7 January 2021

Polyglutamation of methotrexate. Is methotrexate a prodrug?

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7 January 2021

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates

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7 January 2021

Resistance to tomudex (ZD1694): multifactorial in human breast and colon carcinoma cell lines

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7 January 2021

5,10-Dideazatetrahydrofolic acid reduces toxicity and deoxyadenosine triphosphate pool, expansion in cultured L1210 cells treated with inhibitors of thymidylate synthase

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https://api.crossref.org/works/10.1016%2FS0065-2571%2897%2900017-4

7 January 2021

10.1016/S0065-2571(97)00017-4

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DOI

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2 November 2017

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