Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway (Q42537821)

1 November 2017

Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway (English)

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1 November 2017

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Harshil D Dhruv

1

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1 November 2017

Alison Roos

2

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1 November 2017

Patrick J Tomboc

3

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1 November 2017

Serdar Tuncali

4

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1 November 2017

Ashley Chavez

5

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1 November 2017

Ian Mathews

6

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1 November 2017

Michael E Berens

7

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1 November 2017

Joseph C Loftus

8

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1 November 2017

Nhan L Tran

9

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1 November 2017

12 November 2015

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Journal of Neuro-Oncology

1 November 2017

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1 November 2017

126

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1 November 2017

3

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1 November 2017

397-404

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describes a project that uses

1 November 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4733619/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1007/s11060-015-1981-0

0 references

cites work

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Overcoming Drug Development Bottlenecks With Repurposing: Old drugs learn new tricks

28 May 2018

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β-catenin regulates NF-κB activity via TNFRSF19 in colorectal cancer cells

28 May 2018

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The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasio

28 May 2018

1 reference

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TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance.

28 May 2018

1 reference

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A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care

28 May 2018

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The blood-brain/tumor barriers: challenges and chances for malignant gliomas targeted drug delivery

28 May 2018

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Propentofylline targets TROY, a novel microglial signaling pathway

28 May 2018

1 reference

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

28 May 2018

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Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia

28 May 2018

1 reference

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TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling

28 May 2018

1 reference

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Propentofylline: glial modulation, neuroprotection, and alleviation of chronic pain

28 May 2018

1 reference

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A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci

28 May 2018

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Antiangiogenic therapies for high-grade glioma

28 May 2018

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

28 May 2018

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Clonogenic assay of cells in vitro.

28 May 2018

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Tumor necrosis factor receptor superfamily member TROY is a novel melanoma biomarker and potential therapeutic target

28 May 2018

1 reference

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Molecular pathways triggering glioma cell invasion

28 May 2018

1 reference

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Regulation of glioma cell migration by serine-phosphorylated P311

28 May 2018

1 reference

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Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion

28 May 2018

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Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme

28 May 2018

1 reference

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Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis

28 May 2018

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

28 May 2018

1 reference

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Role of synaptojanin 2 in glioma cell migration and invasion

28 May 2018

1 reference

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Expression of a member of tumor necrosis factor receptor superfamily, TROY, in the developing olfactory system.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4733619

Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4733619

Characterization of TNFRSF19, a novel member of the tumor necrosis factor receptor superfamily

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4733619

Propentofylline in the treatment of Alzheimer's disease and vascular dementia: a review of phase III trials

28 May 2018

1 reference

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Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel

28 May 2018

1 reference

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Expression of a member of tumor necrosis factor receptor superfamily, TROY, in the developing mouse brain.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4733619

Propentofylline in the treatment of vascular dementia and Alzheimer-type dementia: overview of phase I and phase II clinical trials.

16 August 2018

1 reference

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A 12-month, randomized, placebo-controlled trial of propentofylline (HWA 285) in patients with dementia according to DSM III-R. The European Propentofylline Study Group.

16 August 2018

1 reference

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The chemoinvasion assay: a method to assess tumor and endothelial cell invasion and its modulation

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11060-015-1981-0

10.1007/S11060-015-1981-0

21 January 2018

Identifiers

DOI

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1 November 2017

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1 November 2017

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