Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13. (Q42525060)

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3 January 2020

title

Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13 (English)

1 reference

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B-cell chronic lymphocytic leukemia

3 January 2020

main subject

arsenic trioxide

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1

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3 January 2020

Andreas Prokesch

8

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3 January 2020

Marcel Scheideler

10

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3 January 2020

9

Christine Papak

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3 January 2020

11

Zlatko Trajanoski

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3 January 2020

3

Daniela Asslaber

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3 January 2020

author name string

Christoph Heyder

2

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3 January 2020

Frank Hamacher

4

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3 January 2020

Inge Tinhofer

5

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3 January 2020

Claudia Holler

6

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3 January 2020

Markus Stöcher

7

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3 January 2020

Richard Greil

12

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3 January 2020

publication date

23 February 2008

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Journal of Molecular Medicine

3 January 2020

published in

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3 January 2020

volume

86

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3 January 2020

issue

5

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3 January 2020

page(s)

541-552

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https://scigraph.springernature.com/pub.10.1007/s00109-008-0314-6

3 January 2020

exact match

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cites work

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-008-0314-6

Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL.

21 January 2018

1 reference

12 December 2020

Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions

1 reference

12 December 2020

Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.

1 reference

12 December 2020

p53 suppression of arsenite-induced mitotic catastrophe is mediated by p21CIP1/WAF1.

1 reference

12 December 2020

Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation

1 reference

12 December 2020

Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia

1 reference

12 December 2020

Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system.

1 reference

12 December 2020

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

1 reference

12 December 2020

Glutathione peroxidase, glutathione reductase, Cu-Zn superoxide dismutase activities, glutathione, nitric oxide, and malondialdehyde concentrations in serum of patients with chronic lymphocytic leukemia

1 reference

12 December 2020

CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells

1 reference

12 December 2020

Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis

1 reference

12 December 2020

Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: correlation with phenotypic characteristics and outcome

1 reference

12 December 2020

Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL.

1 reference

12 December 2020

Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway

1 reference

12 December 2020

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells

1 reference

12 December 2020

Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy

1 reference

12 December 2020

Induction of Mn-superoxide dismutase by Tumor Necrosis Factor, Interleukin-1 and Interleukin-6 in human hepatoma cells

1 reference

12 December 2020

p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression

1 reference

12 December 2020

Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway

1 reference

12 December 2020

Superoxide dismutase as a target for the selective killing of cancer cells

1 reference

12 December 2020

Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia

1 reference

12 December 2020

ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

1 reference

12 December 2020

Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia

1 reference

12 December 2020

Specificity protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression

1 reference

12 December 2020

National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment

1 reference

12 December 2020

Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia

1 reference

12 December 2020

Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications.

1 reference

12 December 2020

Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

1 reference

12 December 2020

Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis

1 reference

12 December 2020

Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy

1 reference

12 December 2020

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

1 reference

12 December 2020

Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway

1 reference

12 December 2020

ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

1 reference

12 December 2020

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

1 reference

12 December 2020

The alteration of mitochondria is an early event of arsenic trioxide induced apoptosis in esophageal carcinoma cells

1 reference

12 December 2020

Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia

1 reference

12 December 2020

Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia

1 reference

12 December 2020