Elevated JNK activation contributes to the pathogenesis of human brain tumors (Q42524158)

1 November 2017

Elevated JNK activation contributes to the pathogenesis of human brain tumors (English)

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1 November 2017

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Marc A Antonyak

1

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1 November 2017

Lawrence C Kenyon

2

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1 November 2017

Andrew K Godwin

3

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1 November 2017

David C James

4

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1 November 2017

David R Emlet

5

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1 November 2017

Isamu Okamoto

6

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1 November 2017

Mehdi Tnani

7

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1 November 2017

Marina Holgado-Madruga

8

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1 November 2017

David K Moscatello

9

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1 November 2017

Albert J Wong

10

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1 November 2017

language of work or name

English

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publication date

1 August 2002

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1 November 2017

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1 November 2017

21

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1 November 2017

5038-5046

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1 November 2017

33

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205593

1 November 2017

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Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

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Constitutive activation of c-Jun N-terminal kinase by a mutant epidermal growth factor receptor

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The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells

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The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells.

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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Shc regulates epidermal growth factor-induced activation of the JNK signaling pathway

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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

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Raf-1 activates MAP kinase-kinase

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The stress-activated protein kinase subfamily of c-Jun kinases

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Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway.

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In situ visualization of intratumor growth factor signaling: immunohistochemical localization of activated ERK/MAP kinase in glial neoplasms

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Regulation of proliferation and apoptosis by epidermal growth factor and protein kinase C in human ovarian surface epithelial cells.

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Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

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Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

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c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

21 January 2018

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Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

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An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

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Protective role for c-Jun in the cellular response to DNA damage

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Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner

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The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin

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Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

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The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation

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Activation of the JNK pathway is essential for transformation by the Met oncogene

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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

21 January 2018

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Hyperexpression of mitogen-activated protein kinase in human breast cancer

21 January 2018

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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

21 January 2018

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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Signaling specificity: the RTK/RAS/MAP kinase pathway in metazoans

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Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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Altered MAP kinase (ERK1,2) regulation in primary cultures of mammary tumor cells: elevated basal activity and sustained response to EGF.

21 January 2018

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Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli

21 January 2018

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The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Transformation of mammalian cells by constitutively active MAP kinase kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205593

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1205593

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Dimensions Publication ID

1 November 2017

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1 reference