glucokinase (Q425185)

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mammalian protein found in Homo sapiens
  • hexokinase D, pancreatic isozyme
  • glucokinase (hexokinase 4)
  • HK IV
  • ATP:D-hexose 6-phosphotransferase
  • HK4
  • GCK
  • hexokinase type IV
  • hexokinase-4
  • Hexokinase-D
edit
Language Label Description Also known as
English
glucokinase
mammalian protein found in Homo sapiens
  • hexokinase D, pancreatic isozyme
  • glucokinase (hexokinase 4)
  • HK IV
  • ATP:D-hexose 6-phosphotransferase
  • HK4
  • GCK
  • hexokinase type IV
  • hexokinase-4
  • Hexokinase-D

Statements

molecular function
glucokinase activity
determination method
IDA
IEA
IMP
TAS
10 references
retrieved
21 June 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
TAS
retrieved
21 June 2018
stated in
Biochemical characterization of novel glucokinase mutations isolated from Spanish maturity-onset diabetes of the young (MODY2) patients.
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IMP
retrieved
21 June 2018
stated in
Activating mutations in the human glucokinase gene revealed by genetic selection
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IMP
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
21 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
21 June 2018
stated in
Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
21 June 2018
stated in
Insights into the pathogenicity of rare missense GCK variants from the identification and functional characterization of compound heterozygous and double mutations inherited in cis
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
21 June 2018
stated in
Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
21 June 2018
stated in
Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IDA
glucokinase activity
determination method
IBA
IDA
IEA
IMP
TAS
11 references
retrieved
7 November 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
TAS
retrieved
7 November 2018
stated in
Biochemical characterization of novel glucokinase mutations isolated from Spanish maturity-onset diabetes of the young (MODY2) patients.
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IMP
retrieved
7 November 2018
stated in
Activating mutations in the human glucokinase gene revealed by genetic selection
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IMP
retrieved
7 November 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
7 November 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
7 November 2018
stated in
Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
7 November 2018
stated in
Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
7 November 2018
stated in
Insights into the pathogenicity of rare missense GCK variants from the identification and functional characterization of compound heterozygous and double mutations inherited in cis
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
7 November 2018
stated in
Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
7 November 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35557&geneProductId=UniProtKB:P35557
determination method
IBA
glucokinase activity
determination method
IBA
IDA
IEA
IMP
10 references
retrieved
8 April 2019
stated in
Biochemical characterization of novel glucokinase mutations isolated from Spanish maturity-onset diabetes of the young (MODY2) patients.
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IMP
retrieved
8 April 2019
stated in
Activating mutations in the human glucokinase gene revealed by genetic selection
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IEA
retrieved
8 April 2019
stated in
Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
8 April 2019
stated in
Insights into the pathogenicity of rare missense GCK variants from the identification and functional characterization of compound heterozygous and double mutations inherited in cis
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
8 April 2019
stated in
Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
8 April 2019
stated in
Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations
GOA
curator
UniProt
UniProt protein ID
P35557
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35557
determination method
IBA
cell component
biological process
Gene Atlas image
PBB GE GCK 211167 s at fs.png
732 × 530; 12 KB
0 references

Identifiers

NE.se ID
glukokinas
0 references
PDB structure ID
 
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