Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis (Q42517588)

1 November 2017

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis (English)

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1 November 2017

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photoreceptor protein

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Crumbs Dmel_CG6383

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GOA release 2020-03-11

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Milena Pellikka

1

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1 November 2017

Guy Tanentzapf

2

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1 November 2017

Madalena Pinto

3

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1 November 2017

Christian Smith

4

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1 November 2017

C Jane McGlade

5

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1 November 2017

Donald F Ready

6

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1 November 2017

Ulrich Tepass

7

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1 November 2017

language of work or name

English

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publication date

17 February 2002

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1 November 2017

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416

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143-149

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1 November 2017

6877

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https://scigraph.springernature.com/pub.10.1038/nature721

1 November 2017

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cites work

Epithelial cell polarity and cell junctions in Drosophila

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Integrins and the development of three-dimensional structure in the Drosophila compound eye.

21 January 2018

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crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia.

21 January 2018

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Phenotypic and developmental analysis of mutations at thecrumbs locus, a gene required for the development of epithelia inDrosophila melanogaster

21 January 2018

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Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila.

21 January 2018

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Crumbs, a component of the apical membrane, is required for zonula adherens formation in primary epithelia of Drosophila.

21 January 2018

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Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12)

21 January 2018

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Leber congenital amaurosis and retinitis pigmentosa with Coats-like exudative vasculopathy are associated with mutations in the crumbs homologue 1 (CRB1) gene

21 January 2018

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Mutations in the CRB1 gene cause Leber congenital amaurosis

21 January 2018

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CRB1 has a cytoplasmic domain that is functionally conserved between human and Drosophila

21 January 2018

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A conserved motif in Crumbs is required for E-cadherin localisation and zonula adherens formation in Drosophila.

21 January 2018

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Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity

21 January 2018

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Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.

21 January 2018

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Site-specific recombination between homologous chromosomes in Drosophila.

21 January 2018

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Spectrin: the ghost in the machine

21 January 2018

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armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila.

21 January 2018

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Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts

21 January 2018

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DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

21 January 2018

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Retinitis pigmentosa: defined from a molecular point of view

21 January 2018

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Molecular genetics and prospects for therapy of the inherited retinal dystrophies

21 January 2018

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The spectrin-based membrane skeleton and micron-scale organization of the plasma membrane

21 January 2018

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Annexin VI-mediated loss of spectrin during coated pit budding is coupled to delivery of LDL to lysosomes

21 January 2018

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A requirement for ankyrin binding to clathrin during coated pit budding

21 January 2018

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Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

21 January 2018

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Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins

21 January 2018

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Cloning of the CDNA for a novel photoreceptor membrane protein (rom-1) identifies a disk rim protein family implicated in human retinopathies

21 January 2018

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Localization of peripherin/rds in the disk membranes of cone and rod photoreceptors: relationship to disk membrane morphogenesis and retinal degeneration

21 January 2018

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Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis

21 January 2018

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Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins

21 January 2018

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Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity.

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Histopathology of the human retina in retinitis pigmentosa

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE721

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Dimensions Publication ID

1 November 2017

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