Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease. (Q42517324)

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7 December 2019

title

Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease (English)

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7 December 2019

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Isabel Lastres-Becker

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7 December 2019

author name string

Henrik H Hansen

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Fernando Berrendero

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Rosario De Miguel

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Alberto Pérez-Rosado

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Jorge Manzanares

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José A Ramos

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Javier Fernández-Ruiz

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publication date

1 April 2002

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7 December 2019

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7 December 2019

volume

44

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7 December 2019

page(s)

23-35

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7 December 2019

issue

1

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3-Nitropropionic acid's lethal triplet: cooperative pathways of neurodegeneration.

7 December 2019

cites work

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Aging, energy, and oxidative stress in neurodegenerative diseases.

21 January 2018

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Functional role of high-affinity anandamide transport, as revealed by selective inhibition

21 January 2018

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Systemic 3-nitropropionic acid: behavioral deficits and striatal damage in adult rats

21 January 2018

1 reference

Hyperactivity and hypoactivity in a rat model of Huntington's disease: the systemic 3-nitropropionic acid model

21 January 2018

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Adjuncts to dopamine replacement: a pragmatic approach to reducing the problem of dyskinesia in Parkinson's disease

21 January 2018

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Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid.

21 January 2018

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Presynaptic inhibition of GABAergic inputs to rat substantia nigra pars reticulata neurones by a cannabinoid agonist.

21 January 2018

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Brain cannabinoid systems as targets for the therapy of neurological disorders

21 January 2018

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Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents.

21 January 2018

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Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington's disease mice

21 January 2018

1 reference

Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease

21 January 2018

1 reference

Advances in Huntington's disease: implications for experimental therapeutics

21 January 2018

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Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent.

21 January 2018

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Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404.

21 January 2018

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Loss of cannabinoid receptors in the substantia nigra in Huntington's disease.

21 January 2018

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The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease

21 January 2018

1 reference

Extrapyramidal and neuroendocrine effects of AM404, an inhibitor of the carrier-mediated transport of anandamide.

21 January 2018

1 reference

Quantifiable bradykinesia, gait abnormalities and Huntington's disease-like striatal lesions in rats chronically treated with 3-nitropropionic acid

21 January 2018

1 reference

Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.

21 January 2018

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Neuron-specific enolase (NSE) and non-neuronal enolase (NNE) mRNAs are co-expressed in neurons of the rat cerebellum: in situ hybridization histochemistry.

21 January 2018

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Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's disease

21 January 2018

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Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry

21 January 2018

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Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55,212-2.

21 January 2018

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Activation of the cannabinoid receptor by delta 9-tetrahydrocannabinol reduces gamma-aminobutyric acid uptake in the globus pallidus.

21 January 2018

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The cannabinoid receptor agonist WIN 55,212-2 reduces D2, but not D1, dopamine receptor-mediated alleviation of akinesia in the reserpine-treated rat model of Parkinson's disease

21 January 2018

1 reference

Huntington chorea is not associated with hyperactivity of nigrostriatal dopaminergic neurons: Studies in postmortem tissues and in rats with kainic acid lesions

21 January 2018

1 reference

Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human

21 January 2018

1 reference

Ipsilateral turning behavior induced by unilateral microinjections of a cannabinoid into the rat subthalamic nucleus.

21 January 2018

1 reference

Fetal tissue transplants in animal models of Huntington's disease: the effects on damaged neuronal circuitry and behavioral deficits

21 January 2018

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Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing

21 January 2018

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Effects of repeated administration of estradiol benzoate on tubero-infundibular GABAergic activity in male rats.

21 January 2018

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Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: implications for neuroprotection studies

21 January 2018

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Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and mu-opioid receptor binding in the basal ganglia.

21 January 2018

1 reference

Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development

21 January 2018

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Differential loss of striatal projection neurons in Huntington disease

21 January 2018

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Differential responses of extracellular GABA to intrastriatal perfusions of 3-nitropropionic acid and quinolinic acid in the rat.

21 January 2018

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Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation

21 January 2018

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Selective vulnerability in Huntington's disease: preferential loss of cannabinoid receptors in lateral globus pallidus.

21 January 2018

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Time-course of the effects of anandamide, the putative endogenous cannabinoid receptor ligand, on extrapyramidal function.

21 January 2018

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The activation of cannabinoid receptors in striatonigral GABAergic neurons inhibited GABA uptake.

21 January 2018

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Unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurons increased CB1 receptor mRNA levels in the caudate-putamen

21 January 2018

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Cannabinoid effects in basal ganglia in a rat model of Parkinson's disease.

21 January 2018

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Comparison of intrastriatal injections of quinolinic acid and 3-nitropropionic acid for use in animal models of Huntington's disease

21 January 2018

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The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)

21 January 2018

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Cannabinoids inhibit excitatory neurotransmission in the substantia nigra pars reticulata

21 January 2018

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Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system

21 January 2018

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Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain

21 January 2018

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The anandamide transport inhibitor AM404 activates vanilloid receptors.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/SYN.10054

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11842443%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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