In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines (Q42509292)

1 November 2017

title

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines (English)

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1 November 2017

18

B R Blazar

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1 November 2017

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C H June

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B L Levine

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1 November 2017

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K L Hippen

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R S O'Connor

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A M Lemire

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A Saha

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E A Hanse

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N C Tennis

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S C Merkel

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A Kelekar

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J L Riley

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L A Turka

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L S Kean

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M L MacMillan

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J S Miller

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J E Wagner

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1 November 2017

D H Munn

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1 November 2017

language of work or name

English

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publication date

4 May 2017

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American Journal of Transplantation

1 November 2017

published in

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Human T regulatory cell therapy: take a billion or so and call me in the morning

1 November 2017

cites work

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Advances in graft-versus-host disease biology and therapy

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T regulatory cells in autoimmune diabetes: past challenges, future prospects

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Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

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Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

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Clinical perspectives for regulatory T cells in transplantation tolerance

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A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity

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Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

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Regulatory T cell reprogramming toward a Th2-cell-like lineage impairs oral tolerance and promotes food allergy

21 January 2018

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The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

21 January 2018

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Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells

21 January 2018

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Prevention of allogeneic fetal rejection by tryptophan catabolism

21 January 2018

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Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

21 January 2018

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Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice

21 January 2018

1 reference

Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice

21 January 2018

1 reference

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

21 January 2018

1 reference

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

21 January 2018

1 reference

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

21 January 2018

1 reference

Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

21 January 2018

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Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

21 January 2018

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An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos.

21 January 2018

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Metabolic regulation of T lymphocytes

21 January 2018

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Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules.

21 January 2018

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Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

21 January 2018

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

21 January 2018

1 reference

IL-7 modulates in vitro and in vivo human memory T regulatory cell functions through the CD39/ATP axis.

21 January 2018

1 reference

Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease

21 January 2018

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

21 January 2018

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From Krebs to clinic: glutamine metabolism to cancer therapy.

21 January 2018

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CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis.

21 January 2018

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A guide to immunometabolism for immunologists.

21 January 2018

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Synchronizing transcriptional control of T cell metabolism and function

21 January 2018

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Fatty acid metabolism in the regulation of T cell function

21 January 2018

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Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.

21 January 2018

1 reference

IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity

21 January 2018

1 reference

Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment

21 January 2018

1 reference

Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells.

21 January 2018

1 reference

Interleukin-2 and regulatory T cells in graft-versus-host disease

21 January 2018

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Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis

21 January 2018

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Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity.

21 January 2018

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IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

21 January 2018

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Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

21 January 2018

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Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

21 January 2018

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HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse.

21 January 2018

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Aryl hydrocarbon receptor (AHR) regulation of L-Type Amino Acid Transporter 1 (LAT-1) expression in MCF-7 and MDA-MB-231 breast cancer cells

21 January 2018

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Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

21 January 2018

1 reference

The end and after: how dying cells impact the living organism

21 January 2018

1 reference

Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells

21 January 2018

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Human CD39hi regulatory T cells present stronger stability and function under inflammatory conditions

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5671378

Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

3 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28470889

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

From Krebs to clinic: glutamine metabolism to cancer therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28470889

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28470889

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/AJT.14338

1 reference

1 November 2017

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