Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine (Q42494150)

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English	Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

1 reference

based on heuristic

inferred from title

tumour xenograft

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based on heuristic

inferred from title

author name string

M E Dolan

1

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

G L Larkin

2

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

H F English

3

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

A E Pegg

4

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

publication date

1 January 1989

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Europe PubMed Central

PubMed publication ID

1 November 2017

Cancer Chemotherapy and Pharmacology

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Europe PubMed Central

PubMed publication ID

1 November 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

2

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Europe PubMed Central

PubMed publication ID

1 November 2017

103-108

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Europe PubMed Central

PubMed publication ID

1 November 2017

https://scigraph.springernature.com/pub.10.1007/bf00692348

0 references

Use of oligodeoxynucleotides containing O6-alkylguanine for the assay of O6-alkylguanine-DNA-alkyltransferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity of human cell strains having different abilities to repair O6-methylguanine in DNA to inactivation by alkylating agents including chloroethylnitrosoureas

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of O6-ethylguanine in DNA by a chromatin fraction from rat liver: transfer of the ethyl group to an acceptor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chloroethylnitrosourea cancer chemotherapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of synthetic oligonucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine, by O6-alkylguanine-DNA alkyltransferase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligodeoxynucleotides as inhibitors of gene expression: a review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of oligodeoxynucleotides containing O6-methylguanine by O6-alkylguanine-DNA-alkyltransferase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of O6-alkylguanine pretreatment on the sensitivity of human colon tumor cells to the cytotoxic effects of chloroethylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of O6-alkylguanine-DNA alkyltransferase activity in human cells and tumor tissues by restriction endonuclease inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased cytotoxicity of 1-(2-chloroethyl)-1-nitroso-3(4-methyl)-cyclohexylurea by pretreatment with O6-methylguanine in resistant but not in sensitive human melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Removal of O6-methylguanine from DNA by human liver fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of cross-link formation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and properties of O6-methylguanine-DNA transmethylase from rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of O6-alkylguanine-DNA alkyltransferase activity in HeLa cells treated with O6-alkylguanines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Techniques for using antisense oligodeoxyribonucleotides to study gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between O6-methylguanine-DNA-methyltransferase activity and resistance of human cells to the cytotoxic and mutagenic effect of N-methyl-N'-nitro-N-nitrosoguanidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-linking of DNA induced by chloroethyinitrosourea is prevented by O6-methyiguanine-DNA methyttransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of O6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of O6-alkylguanine-DNA alkyltransferase in the rat liver due to an intraperitoneal administration of methylated DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of the cross-link 1-[N3-deoxycytidyl),2-[N1-deoxyguanosinyl]ethane in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of O6-propylguanine and O6-butylguanine in DNA by O6-alkylguanine-DNA alkyltransferases from rat liver and E. coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapy of human colon cancer xenografts in athymic nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

O6-alkylguanine-DNA alkyltransferase activity in normal human tissues and cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

6-Methylguanine and 6-methylguanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line but not in other xeroderma pigmentosum and normal human fibroblast strains after treatment with 1-(2-chloroethyl)-1-nitroso-3-(2-hydr

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCNU (NSC-409962) in the treatment of advanced Hodgkin's disease: its role in remission induction and maintenance

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of O6-alkylguanine-DNA-alkyltransferase activity potentiates cytotoxicity and induction of SCEs in human glioma cells resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytotoxic and mutagenic effects of alkylating agents on human lymphoid cells are caused by different DNA lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pretreatment of human colon tumor cells with DNA methylating agents inhibits their ability to repair chloroethyl monoadducts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of nitrosourea cytotoxicity in human leukemic cells by inactivation of O6-alkylguanine-DNA alkyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of O6-methylguanine-DNA methyltransferase and sensitization of human tumor cells to killing by chloroethylnitrosourea by O6-methylguanine as a free base.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential repair of 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea-induced DNA damage in two human colon tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure of HeLa cells to 0(6)-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple, rapid, and sensitive DNA assay procedure

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA-protein cross-linking and DNA interstrand cross-linking by haloethylnitrosoureas in L1210 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2557168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00692348

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

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