The platelet-activating factor receptor antagonist L-659,989 inhibits phospholipase D activity. (Q42471927)

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7 December 2019

title

The platelet-activating factor receptor antagonist L-659,989 inhibits phospholipase D activity (English)

1 reference

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7 December 2019

author name string

A Gómez-Muñoz

series ordinal

1

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7 December 2019

L O'Brien

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10320807%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

U P Steinbrecher

series ordinal

3

1 reference

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7 December 2019

publication date

1 May 1999

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Biochimica et Biophysica Acta

7 December 2019

published in

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7 December 2019

volume

1438

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7 December 2019

issue

2

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7 December 2019

page(s)

247-252

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(+/-)-trans-2-(3-Methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5- trimethoxyphenyl)tetrahydrofuran (L-659,989), a novel, potent PAF receptor antagonist

7 December 2019

cites work

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PAF mediates neutrophil adhesion to thrombin or TNF-stimulated endothelial cells under shear stress

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Platelet-activating factor antagonism improves ventricular contractility in endotoxemia

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Differing roles for platelet-activating factor during inflammation of the lung and subarachnoid space. The special case of Streptococcus pneumoniae.

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7 January 2021

Phospholipase D: enzymology, mechanisms of regulation, and function

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Phospholipid signaling

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Stimulation of actin stress fibre formation mediated by activation of phospholipase D

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Correlation between secretion and phospholipase D activation in differentiated HL60 cells.

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7 January 2021

Induction of in vitro tumor cell invasion of cellular monolayers by lysophosphatidic acid or phospholipase D.

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7 January 2021

Stimulation of DNA synthesis by natural ceramide 1-phosphate

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Modulation of cell signalling by ceramides.

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"Cross talk" between the bioactive glycerolipids and sphingolipids in signal transduction

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Lysophosphatidic acid, a multifunctional phospholipid messenger

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7 January 2021

Interaction of Ceramides, Sphingosine, and Sphingosine 1-Phosphate in Regulating DNA Synthesis and Phospholipase D Activity

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7 January 2021

Changing J774A.1 cells to new medium perturbs multiple signaling pathways, including the modulation of protein kinase C by endogenous sphingoid bases

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7 January 2021

Differential roles of de novo sphingolipid biosynthesis and turnover in the "burst" of free sphingosine and sphinganine, and their 1-phosphates and N-acyl-derivatives, that occurs upon changing the medium of cells in culture

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7 January 2021

Chromogenic assay for phospholipase D from Streptomyces chromofuscus: application to the evaluation of substrate analogs

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7 January 2021

Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha

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7 January 2021

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

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7 January 2021

Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis.

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Differential effects of sphingomyelinase and cell-permeable ceramide analogs on proliferation of Swiss 3T3 fibroblasts

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7 January 2021

10.1016/S1388-1981(99)00056-6

Identifiers

DOI

1 reference

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7 December 2019

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