IGFBP-3 activates TGF-beta receptors and directly inhibits growth in human intestinal smooth muscle cells (Q42462619)

1 November 2017

IGFBP-3 activates TGF-beta receptors and directly inhibits growth in human intestinal smooth muscle cells (English)

1 reference

1 November 2017

John F Kuemmerle

1

1 reference

PubMed ID

15178549

1 November 2017

Karnam S Murthy

series ordinal

2

1 reference

PubMed ID

15178549

1 November 2017

Jennifer G Bowers

series ordinal

3

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1 November 2017

3 June 2004

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American Journal of Physiology - Gastrointestinal and Liver Physiology

1 November 2017

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1 November 2017

287

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1 November 2017

4

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1 November 2017

G795-802

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Signalling pathways involved in antiproliferative effects of IGFBP-3: a review

1 November 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Growth inhibition by insulin-like growth factor-binding protein-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-beta ) and the type II TGF-beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Regulation of vascular smooth muscle cell responses to insulin-like growth factor (IGF)-I by local IGF-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Cellular growth inhibition by IGFBP-3 and TGF-beta1 requires LRP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

IGFBP-3 mediates TGF beta 1 proliferative response in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Reduced serum insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 levels in adults with inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Autocrine regulation of growth in cultured human intestinal muscle by growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gi2 in human intestinal smooth muscle: Gbetagamma -dependent mitogen-activated protein kinase activation and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Insulin-like growth factor-binding protein-5 (IGFBP-5) stimulates growth and IGF-I secretion in human intestinal smooth muscle by Ras-dependent activation of p38 MAP kinase and Erk1/2 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

IGF-I stimulates human intestinal smooth muscle cell growth by regulation of G1phase cell cycle proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Inflammation location, but not type, determines the increase in TGF-beta1 and IGF-1 expression and collagen deposition in IBD intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

A non-IGF binding mutant of IGFBP-3 modulates cell function in breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Antiproliferative effects of insulin-like growth factor-binding protein-3 in mesenchymal chondrogenic cell line RCJ3.1C5.18. relationship to differentiation stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Characterization of the MADH2/Smad2 gene, a human Mad homolog responsible for the transforming growth factor-beta and activin signal transduction pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Selective expression of vasoactive intestinal peptide (VIP)2/pituitary adenylate cyclase-activating polypeptide (PACAP)3 receptors in rabbit and guinea pig gastric and tenia coli smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

Normal growth and development in the absence of hepatic insulin-like growth factor I

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00009.2004

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00009.2004

1 reference

1 November 2017

1 reference

PubMed ID

15178549