A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII. (Q42452421)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24421356%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII (English)

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5 March 2020

1 reference

1 reference

4

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5 March 2020

Stefano Morotti

1

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5 March 2020

Eleonora Grandi

5

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5 March 2020

author name string

A G Edwards

2

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5 March 2020

A D McCulloch

3

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5 March 2020

language of work or name

English

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publication date

13 January 2014

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5 March 2020

published in

Journal of Physiology

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5 March 2020

volume

592

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5 March 2020

issue

6

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5 March 2020

page(s)

1181-1197

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Ranolazine for congenital and acquired late INa-linked arrhythmias: in silico pharmacological screening.

5 March 2020

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Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

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Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδ(C) can be reversed by inhibition of late Na(+) current

30 September 2018

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30 September 2018

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A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

30 September 2018

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30 September 2018

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30 September 2018

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30 September 2018

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30 September 2018

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30 September 2018

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30 September 2018

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30 September 2018

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Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure

30 September 2018

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30 September 2018

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A mathematical treatment of integrated Ca dynamics within the ventricular myocyte.

30 September 2018

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30 September 2018

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30 September 2018

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30 September 2018

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30 September 2018

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Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release

30 September 2018

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Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model

30 September 2018

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Effect of androgen deficiency on mouse ventricular repolarization

30 September 2018

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Mechanisms underlying the frequency dependence of contraction and [Ca(2+)](i) transients in mouse ventricular myocytes

30 September 2018

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Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged

30 September 2018

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Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness

30 September 2018

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30 September 2018

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30 September 2018

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Effects of overexpression of the Na+-Ca2+ exchanger on [Ca2+]i transients in murine ventricular myocytes

30 September 2018

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Overexpression of CaMKIIδc in RyR2R4496C+/- knock-in mice leads to altered intracellular Ca2+ handling and increased mortality

30 September 2018

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12 December 2020

Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects

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12 December 2020

Influence of prior Na+ pump activity on pump and Na+/Ca2+ exchange currents in mouse ventricular myocytes

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Glucocorticoid regulation of cardiac K+ currents and L-type Ca2+ current in neonatal mice

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Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failure

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12 December 2020

Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias

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12 December 2020

Remodelling of ionic currents in hypertrophied and failing hearts of transgenic mice overexpressing calsequestrin

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Intracellular [Na+] and Na+ pump rate in rat and rabbit ventricular myocytes

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