Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment (Q42438111)

31 October 2017

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment (English)

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31 October 2017

7

Donald E Ingber

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31 October 2017

6

Kahp-Yang Suh

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31 October 2017

Kyung-Jin Jang

1

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31 October 2017

Ali Poyan Mehr

2

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31 October 2017

Geraldine A Hamilton

3

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31 October 2017

Lori A McPartlin

4

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31 October 2017

Seyoon Chung

5

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31 October 2017

1 September 2013

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31 October 2017

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31 October 2017

5

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31 October 2017

9

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31 October 2017

1119-1129

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Next-generation biomarkers for detecting kidney toxicity

31 October 2017

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https://api.crossref.org/works/10.1039%2FC3IB40049B

How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Renal vulnerability to drug toxicity

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Drug-induced acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Comparison of the novel HK-2 human renal proximal tubular cell line with the standard LLC-PK1 cell line in studying drug-induced nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Toxicology investigations with cell culture systems: 20 years after.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Cell lines with extended in vitro growth potential from human renal proximal tubule: characterization, response to inducers, and comparison with established cell lines

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Calcium sensitivity of dicarboxylate transport in cultured proximal tubule cells

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

The paracellular permeability of opossum kidney cells, a proximal tubule cell line

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Mechanosensory function of microvilli of the kidney proximal tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Microengineered physiological biomimicry: organs-on-chips.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

The use of controlled surface topography and flow-induced shear stress to influence renal epithelial cell function

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Fluid-shear-stress-induced translocation of aquaporin-2 and reorganization of actin cytoskeleton in renal tubular epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Impact of drug transporter studies on drug discovery and development

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Species differences in drug transporters and implications for translating preclinical findings to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Infolded basal plasma membranes found in epithelia noted for their water transport

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Cystic kidney diseases: all roads lead to the cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Renal primary cilia lengthen after acute tubular necrosis

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Transport of metabolic substrates by the proximal nephron

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Renal albumin absorption in physiology and pathology

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Model of albumin reabsorption in the proximal tubule

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Cisplatin nephrotoxicity: a review

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Cisplatin nephrotoxicity: mechanisms and renoprotective strategies

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Mechanisms of Cisplatin nephrotoxicity

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Nephrotoxicity of platinum complexes is related to basolateral organic cation transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Cisplatin-induced cytotoxicity in BSO-exposed renal proximal tubular epithelial cells: sex, age, and species

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Possible role of cysteine-S-conjugate β-lyase in species differences in cisplatin nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Characterization of P-glycoprotein and multidrug resistance proteins in rat kidney and intestinal cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Drug interaction studies: study design, data analysis, and implications for dosing and labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

A primary culture of mouse proximal tubular cells, established on collagen-coated membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

The role of preclinical animal models in breast cancer drug development

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3IB40049B

Role of animal models in the study of drug-induced hypersensitivity reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Clinical development of platinum complexes in cancer therapy: an historical perspective and an update.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

Reconstituting organ-level lung functions on a chip

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

NIH Image to ImageJ: 25 years of image analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

A Fibrin-Based Tissue-Engineered Renal Proximal Tubule for Bioartificial Kidney Devices: Development, Characterization andIn VitroTransport Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3IB40049B

21 January 2018

Identifiers

DOI

10.1039/C3IB40049B

1 reference

31 October 2017

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