Jump to content

tadalafil (Q424156)

From Wikidata
active substance for the treatment of erectile dysfunction, prostate enlargement and pulmonary hypertension
  • Adcirca®
  • Cialis®
  • IC-351
  • IC351
  • (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
  • (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
  • (6R,12AR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
  • Tadanafil
  • ICOS 351
  • 6-BENZO[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
edit
Language Label Description Also known as
default for all languages
No label defined
    English
    tadalafil
    active substance for the treatment of erectile dysfunction, prostate enlargement and pulmonary hypertension
    • Adcirca®
    • Cialis®
    • IC-351
    • IC351
    • (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
    • (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
    • (6R,12AR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
    • Tadanafil
    • ICOS 351
    • 6-BENZO[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

    Statements

    has use
    medication
    0 references
    mass
    389.138 dalton
    1 reference
    stated in
    PubChem
    PubChem CID
    110635
    language of work or name
    English
    title
    Tadalafil (English)
    retrieved
    19 October 2016
    chemical formula
    C₂₂H₁₉N₃O₄
    1 reference
    stated in
    PubChem
    PubChem CID
    110635
    language of work or name
    English
    title
    Tadalafil (English)
    retrieved
    19 November 2016
    canonical SMILES
    CN1CC(=O)N2C(C1=O)CC3=C(C2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36
    1 reference
    stated in
    PubChem
    PubChem CID
    110635
    language of work or name
    English
    title
    Tadalafil (English)
    retrieved
    19 November 2016
    isomeric SMILES
    CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36
    1 reference
    stated in
    PubChem
    PubChem CID
    110635
    language of work or name
    English
    title
    Tadalafil (English)
    retrieved
    19 November 2016
    significant drug interaction
    legal status (medicine)
    boxed warning
    1 reference
    reference URL
    https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
    title
    FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)
    Commons category
    Tadalafil
    0 references

    Identifiers

    Reaxys registry number
    9589181
    1 reference
    stated in
    ChEBI
    ChEBI ID
    71940
    language of work or name
    English
    title
    tadalafil (English)
    retrieved
    19 October 2016
    HSDB ID
    7303
    1 reference
    stated in
    Hazardous Substances Data Bank
    HSDB ID
    7303
    publication date
    28 October 2019
    title
    TADALAFIL (English)
    retrieved
    10 May 2021
    LiverTox ID
    Tadalafil
    0 references
    NSC number
    759172
    0 references
    750236
    0 references
    EC number
    687-782-2
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.214.024
    retrieved
    27 December 2018
    title
    (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁶]heptadeca-1(10),11,13,15-tetraene-4,7-dione (English)
    quotation
    CAS no.: 171596-29-5 (English)
    ECHA Substance Infocard ID
    100.214.024
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.214.024
    retrieved
    27 December 2018
    title
    (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁶]heptadeca-1(10),11,13,15-tetraene-4,7-dione (English)
    quotation
    CAS no.: 171596-29-5 (English)
    KEGG ID
    D02008
    1 reference
    stated in
    ChEBI
    ChEBI ID
    71940
    language of work or name
    English
    title
    tadalafil (English)
    retrieved
    19 October 2016
    PDB ligand ID
    CIA
    0 references
    DeCS ID
    55926
    0 references
    WordNet 3.1 Synset ID
    04390624-n
    1 reference
    stated in
    GF WordNet
     
    edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q424156&oldid=2294991286"