Development of a facile antibody-drug conjugate platform for increased stability and homogeneity (Q42293596)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28451344%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Development of a facile antibody-drug conjugate platform for increased stability and homogeneity (English)

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19 March 2020

1

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19 March 2020

Monideepa Roy

13

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19 March 2020

Shiladitya Sengupta

14

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19 March 2020

12

Swadhin K Mandal

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19 March 2020

author name string

Johny Kancharla

2

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19 March 2020

Shelly Kaushik

3

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19 March 2020

Aasif Ansari

4

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19 March 2020

Samad Hossain

5

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19 March 2020

Ravinder Goyal

6

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19 March 2020

Manoj Pandey

7

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19 March 2020

Jwala Sivaccumar

8

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19 March 2020

Sazid Hussain

9

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19 March 2020

Arindam Sarkar

10

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19 March 2020

Aniruddha Sengupta

11

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19 March 2020

publication date

9 December 2016

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19 March 2020

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19 March 2020

volume

8

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19 March 2020

page(s)

2387-2395

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19 March 2020

issue

3

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New developments for antibody-drug conjugate-based therapeutic approaches

19 March 2020

cites work

1 reference

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Field Guide to Challenges and Opportunities in Antibody-Drug Conjugates for Chemists.

26 October 2017

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A Polymer-Based Antibody-Vinca Drug Conjugate Platform: Characterization and Preclinical Efficacy

26 October 2017

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Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC).

26 October 2017

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Current ADC Linker Chemistry

26 October 2017

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Improving the therapeutic index in cancer therapy by using antibody-drug conjugates designed with a moderately cytotoxic drug

26 October 2017

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Methods for site-specific drug conjugation to antibodies

26 October 2017

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Synthesis of site-specific antibody-drug conjugates using unnatural amino acids

26 October 2017

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Designing immunoconjugates for cancer therapy

26 October 2017

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Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.

26 October 2017

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Antibody-drug conjugates: linking cytotoxic payloads to monoclonal antibodies.

26 October 2017

1 reference

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Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.

26 October 2017

1 reference

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Novel humanized anti-CD20 monoclonal antibodies with unique germline VH and VL gene recruitment and potent effector functions

26 October 2017

1 reference

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Contribution of linker stability to the activities of anticancer immunoconjugates

26 October 2017

1 reference

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Monoclonal antibody cetuximab binds to and down-regulates constitutively activated epidermal growth factor receptor vIII on the cell surface.

26 October 2017

1 reference

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The role of sulfur in platinum anticancer chemotherapy

26 October 2017

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Interactions of antitumor metallodrugs with serum proteins: advances in characterization using modern analytical methodology.

26 October 2017

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Platinum(II) complexes with antitumoral/antiviral aromatic heterocycles: effect of glutathione upon in vitro cell growth inhibition

26 October 2017

1 reference

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Paul Ehrlich's magic bullets

26 October 2017

1 reference

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Development of Herceptin resistance in breast cancer cells

26 October 2017

1 reference

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Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase

26 October 2017

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20-O-acylcamptothecin derivatives: evidence for lactone stabilization.

29 May 2018

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Ado-trastuzumab Emtansine (T-DM1): an antibody-drug conjugate (ADC) for HER2-positive breast cancer.

29 May 2018

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Statistical modeling of the drug load distribution on trastuzumab emtansine (Kadcyla), a lysine-linked antibody drug conjugate.

17 August 2018

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Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma

17 August 2018

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Cisplatin interaction with cysteine and methionine, a theoretical DFT study

17 August 2018

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Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody-Drug Conjugate SYD985.

17 August 2018

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Crossref

https://api.crossref.org/works/10.1039%2FC6SC05149A

195Pt NMR spectroscopy: A chemometric approach

21 January 2018

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Crossref

https://api.crossref.org/works/10.1039%2FC6SC05149A

Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate

21 January 2018

1 reference

12 December 2020

The structural basis of camptothecin interactions with human serum albumin: impact on drug stability

1 reference

12 December 2020

The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma

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12 December 2020

Platinum(II) as bifunctional linker in antibody-drug conjugate formation: coupling of a 4-nitrobenzo-2-oxa-1,3-diazole fluorophore to trastuzumab as a model

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12 December 2020

Randomized phase II study of BR96-doxorubicin conjugate in patients with metastatic breast cancer

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12 December 2020

Identifiers

DOI

10.1039/C6SC05149A

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28451344%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28451344%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference