Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps. (Q42290699)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28373542%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

title

Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps (English)

1 reference

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15 March 2020

6

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15 March 2020

Yit-Heng Chooi

10

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15 March 2020

author name string

Xiaoqing Zheng

1

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15 March 2020

Qiuxiang Cheng

2

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15 March 2020

Fen Yao

3

1 reference

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15 March 2020

Xiaozheng Wang

4

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15 March 2020

Lingxin Kong

5

1 reference

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15 March 2020

Min Xu

7

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15 March 2020

Shuangjun Lin

8

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15 March 2020

Zixin Deng

9

1 reference

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15 March 2020

Delin You

11

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15 March 2020

language of work or name

English

0 references

publication date

3 April 2017

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15 March 2020

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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15 March 2020

volume

114

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15 March 2020

page(s)

4135-4140

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15 March 2020

issue

16

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Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp.

15 March 2020

cites work

1 reference

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antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

26 October 2017

1 reference

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Detecting sequence homology at the gene cluster level with MultiGeneBlast

26 October 2017

1 reference

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Unveiling the post-PKS redox tailoring steps in biosynthesis of the type II polyketide antitumor antibiotic xantholipin

26 October 2017

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Prephenate aminotransferase directs plant phenylalanine biosynthesis via arogenate.

26 October 2017

1 reference

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Glycerol utilization gene cluster in Streptomyces clavuligerus

26 October 2017

1 reference

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A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis

26 October 2017

1 reference

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Biological formation of pyrroles: nature's logic and enzymatic machinery

26 October 2017

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Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval

26 October 2017

1 reference

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A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402462

Identification of anisomycin-activated kinases p45 and p55 in murine cells as MAPKAP kinase-2.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402462

Escherichia coli aromatic amino acid aminotransferase: characterization and comparison with aspartate aminotransferase

26 October 2017

1 reference

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Metabolism of Proline and the Hydroxyprolines

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402462

Inhibitors of protein biosynthesis. II. Mode of action of anisomycin

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402462

Anisomycin. II.1 Biosynthesis of Anisomycin

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402462

Memory: Modification of Anisomycin-Induced Amnesia by Stimulants and Depressants

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402462

A Multifunctional Monooxygenase XanO4 Catalyzes Xanthone Formation in Xantholipin Biosynthesis via a Cryptic Demethoxylation.

26 October 2017

1 reference

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Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate

29 May 2018

1 reference

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Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402462

Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms.

17 August 2018

1 reference

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Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

17 August 2018

1 reference

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Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomy

17 August 2018

1 reference

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Application of Pd(0)-catalyzed intramolecular oxazine formation to the efficient total synthesis of (-)-anisomycin

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28373542

12 December 2020

inferred from PubMed ID database lookup

Characterization of streptonigrin biosynthesis reveals a cryptic carboxyl methylation and an unusual oxidative cleavage of a N-C bond

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28373542

12 December 2020

inferred from PubMed ID database lookup

Anisomycin and new congeners active against human tumor cell lines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28373542

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1701361114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28373542%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

1 reference

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15 March 2020

1 reference