Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients. (Q42280014)

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scientific article published on August 2013

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English	Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients.	scientific article published on August 2013

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6 March 2020

Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients (English)

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6 March 2020

Alexander Scheffold

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6 March 2020

Mario Assenmacher

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Mario Assenmacher

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6 March 2020

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Anna Casati

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6 March 2020

Azam Varghaei-Nahvi

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6 March 2020

Steven Alexander Feldman

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6 March 2020

Steven Aaron Rosenberg

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6 March 2020

Mark Edward Dudley

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6 March 2020

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1 August 2013

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6 March 2020

Cancer Immunology, Immunotherapy

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6 March 2020

62

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6 March 2020

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6 March 2020

1563-1573

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6 March 2020

https://scigraph.springernature.com/pub.10.1007/s00262-013-1459-x

0 references

Adoptive immunotherapy for cancer: harnessing the T cell response

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Adoptive T cell therapy of cancer

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Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

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Cancer regression in patients after transfer of genetically engineered lymphocytes

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Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

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T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

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Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice

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Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

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Immune responses to transgene and retroviral vector in patients treated with ex vivo-engineered T cells

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Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes

1 reference

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21 January 2018

Adoptive immunotherapy for cancer: building on success

1 reference

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21 January 2018

Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.

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21 January 2018

Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity.

1 reference

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21 January 2018

Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

1 reference

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21 January 2018

Optimization of culture conditions for activation and large-scale expansion of human T lymphocytes for bispecific antibody-directed cellular immunotherapy

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Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation

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Selected murine residues endow human TCR with enhanced tumor recognition

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21 January 2018

High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes

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21 January 2018

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21 January 2018

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1 reference

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21 January 2018

Modulation by IL-2 of CD70 and CD27 expression on CD8+ T cells: importance for the therapeutic effectiveness of cell transfer immunotherapy

1 reference

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21 January 2018

Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regression

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21 January 2018

Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction

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21 January 2018

Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy

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Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

1 reference

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21 January 2018

Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1459-X

21 January 2018

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

1 reference

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21 January 2018

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

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Engraftment of human central memory-derived effector CD8+ T cells in immunodeficient mice

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Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central memory phenotype

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Minimally cultured or selected autologous tumor-infiltrating lymphocytes after a lympho-depleting chemotherapy regimen in metastatic melanoma patients

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Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients

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Pathways of memory CD8+ T-cell development

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IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes

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IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

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T helper 17 cells promote cytotoxic T cell activation in tumor immunity

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21 January 2018

Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1

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Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines

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10.1007/S00262-013-1459-X

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6 March 2020

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6 March 2020

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6 March 2020

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