A recombinant hybrid anaphylatoxin with dual C3a/C5a activity (Q42267186)

19 October 2017

A recombinant hybrid anaphylatoxin with dual C3a/C5a activity (English)

1 reference

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27 September 2022

author name string

Bitter-Suermann D

8

1 reference

19 October 2017

W. Bautsch

1

1 reference

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27 September 2022

T. Kretzschmar

2

1 reference

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27 September 2022

T. Stühmer

3

1 reference

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27 September 2022

A. Kola

4

1 reference

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27 September 2022

M. Emde

5

1 reference

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27 September 2022

J. Köhl

6

1 reference

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27 September 2022

A. Klos

7

1 reference

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27 September 2022

D. Bitter-Suermann

8

1 reference

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27 September 2022

language of work or name

English

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publication date

1 November 1992

1 reference

19 October 2017

15 November 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1445269

full work available at URL

27 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1445269/?tool=EBI

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1445269/pdf/?tool=EBI

27 September 2022

file format

Portable Document Format

online access status

open access

1 reference

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https://europepmc.org/articles/PMC1132107

27 September 2022

1 reference

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https://europepmc.org/articles/PMC1132107?pdf=render

27 September 2022

file format

Portable Document Format

online access status

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27 September 2022

1 reference

19 October 2017

288 ( Pt 1)

1 reference

19 October 2017

261-266

1 reference

Easy identification of cDNA clones

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Clinical utility of complement anaphylatoxin assays.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Secondary structure of complement component C3a anaphylatoxin in solution as determined by NMR spectroscopy: differences between crystal and solution conformations

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

C5a fragment of bovine complement. Purification, bioassays, amino-acid sequence and other structural studies

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Molecular organization and function of the complement system

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Vectors that facilitate the expression and purification of foreign peptides in Escherichia coli by fusion to maltose-binding protein

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Tertiary structure of human complement component C5a in solution from nuclear magnetic resonance data

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

A simple method for site-directed mutagenesis using the polymerase chain reaction

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Isolation and sequence analysis of a cDNA clone encoding the fifth complement component

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Human C5a anaphylatoxin: gene cloning and expression in Escherichia coli

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Immunologic release in the rat peritoneal cavity lipid chemotactic and chemokinetic factors for polymorphonuclear leukocytes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Synthetic peptides with the biological activities and specificity of human C3a anaphylatoxin

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Human plasma carboxypeptidase N. Isolation and characterization

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Release of histamine from rat mast cells by the complement peptides C3a and C5a.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Comparative study on biological activities of various anaphylatoxins (C4a, C3a, C5a). Investigations on their ability to induce platelet secretion.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Synthetic C3a analogs as specific inhibitors of C3a activity.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

The active site of C3a anaphylatoxin.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Circular dichroism of C5a anaphylatoxin of porcine complement

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Guinea pigs deficient in C2, C4, C3 or the C3a receptor.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Demonstration of a specific C3a receptor on guinea pig platelets.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Design and biological activity of a new generation of synthetic C3a analogues by combination of peptidic and non-peptidic elements.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Detection of native human complement components C3 and C5 and their primary activation peptides C3a and C5a (anaphylatoxic peptides) by ELISAs with monoclonal antibodies.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Human C3a-mediated suppression of the immune response. I. Suppression of murine in vitro antibody responses occurs through the generation of nonspecific Lyt-2+ suppressor T cell

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Human C5a anaphylatoxin: gene synthesis, expression, and recovery of biologically active material from Escherichia coli.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Characterization of C3a receptor-proteins on guinea pig platelets and human polymorphonuclear leukocytes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Designing synthetic superagonists of C3a anaphylatoxin

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Characterization of the C5a Receptor on Guinea Pig Platelets

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Improvements in the minimum binding sequence of C5a: examination of His-67

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Structure-function studies in a series of carboxyl-terminal octapeptide analogs of anaphylatoxin C5a

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

C5a structural requirements for neutrophil receptor interaction

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Functional activities of synthetic anaphylatoxic peptides in widely used biological assays

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Platelet-serotonin release by C3a and C5a: two independent pathways of activation.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132107

Reevaluation of the C3a active site using short synthetic C3a analogues

17 August 2018

1 reference

12 December 2020

Characterization of a receptor for C5a anaphylatoxin on human eosinophils

1 reference

12 December 2020

Biological effects of the human complement fragments C5a and C5ades Arg on neutrophil function

1 reference

12 December 2020

An Escherichia coli vector to express and purify foreign proteins by fusion to and separation from maltose-binding protein

1 reference

12 December 2020

Complement C5a receptor antagonism by protamine and poly-L-Arg on human leukocytes

1 reference

12 December 2020

High-level C5a gene expression and recovery of recombinant human C5a from Escherichia coli

1 reference

12 December 2020

In vivo effects of C3a on neutrophils and its contribution to inflammatory lung processes in a guinea-pig model

1 reference

12 December 2020

Anaphylatoxin-mediated regulation of the immune response. II. C5a-mediated enhancement of human humoral and T cell-mediated immune responses

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2880261

1 reference

release_jzu6xlcptvhqvolwd77jgyigvq

19 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jzu6xlcptvhqvolwd77jgyigvq

24 November 2022

mapped directly with Wikidata item

1 reference

19 October 2017

1 reference