Electrophysiological mechanism for the antiarrhythmic action of propafenone: a comparison with mexiletine (Q42258751)

19 October 2017

Electrophysiological mechanism for the antiarrhythmic action of propafenone: a comparison with mexiletine (English)

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19 October 2017

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Amerini S

1

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19 October 2017

Bernabei R

2

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19 October 2017

Carbonin P

3

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19 October 2017

Cerbai E

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19 October 2017

Mugelli A

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19 October 2017

Pahor M

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19 October 2017

language of work or name

English

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publication date

1 December 1988

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British Journal of Pharmacology

19 October 2017

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19 October 2017

95

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19 October 2017

4

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19 October 2017

1039-1046

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A low-cost microcomputer system for automated analysis of intracellular cardiac action potentials

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Inward current channels activated by intracellular Ca in cultured cardiac cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

A Classification of Antiarrhythmic Actions Reassessed After a Decade of New Drugs

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

The multiple modes of action of propafenone

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

The surprising heart: a review of recent progress in cardiac electrophysiology

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Lidocaine's negative inotropic and antiarrhythmic actions. Dependence on shortening of action potential duration and reduction of intracellular sodium activity

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

The effects of tension on acetylstrophanthidin-induced transient depolarizations and aftercontractions in canine myocardial and Purkinje tissues

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Digitalis arrhythmias: role of oscillatory afterpotentials

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

The role of intracellular sodium activity in the anti-arrhythmic action of local anaesthetics in sheep Purkinje fibres

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Effects of Mexiletine on Steady-State Characteristics an Recovery Kinetics of &OV0312;max and Conduction Velocity in Guinea Pig Myocardium

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Electrophysiological and Antiarrhythmic Properties of Propafenon in Isolated Cardiac Preparations

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Inhibiton of $$\dot V_{\max } $$ of the action potential by propafenone and its voltage-, time- and pH-dependence in mammalian ventricular myocardium

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Electrophysiological effects of propafenone on isolated guinea-pig ventricular muscle and sheep Purkinje fibres

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Electrophysiological mechanisms for the antiarrhythmic action of mexiletine on digitalis-, reperfusion- and reoxygenation-induced arrhythmias

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Effect of verapamil and diltiazem on calcium-dependent electrical activity in cardiac Purkinje fibres

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Ionic basis of transient inward current induced by strophanthidin in cardiac Purkinje fibres.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Inhibitory effect of anoxia on reperfusion- and digitalis-induced ventricular tachyarrhythmias

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Maximal upstroke velocity as an index of available sodium conductance. Comparison of maximal upstroke velocity and voltage clamp measurements of sodium current in rabbit Purkinje fibers

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Tonic and phasic INa blockade by antiarrhythmics. Different properties of drug binding to fast sodium channels as judged from Vmax studies with propafenone and derivatives in mammalian ventricular myocardium

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

Resting and rate-dependent depression of maximum rate of depolarisation (Vmax) in guinea pig ventricular action potentials by mexiletine, disopyramide, and encainide.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854270

On the mechanism underlying the oscillatory current in cardiac Purkinje fibers

17 August 2018

1 reference

12 December 2020

Comparison of the effects of regional ischemia, hypoxia, hyperkalemia, and acidosis on intracellular and extracellular potentials and metabolism in the isolated porcine heart

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12 December 2020

An oscillatory current in sheep cardiac Purkinje fibers

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12 December 2020

Potential electrophysiologic mechanisms responsible for dysrhythmias associated with reperfusion of ischemic myocardium

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12 December 2020

Clinical pharmacology of propafenone

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12 December 2020

Barium-induced spontaneous activity in sheep cardiac Purkinje cells

1 reference

12 December 2020

The time course of action potential repolarization affects delayed afterdepolarization amplitude in atrial fibers of the canine coronary sinus

1 reference

12 December 2020

Reperfusion-induced arrhythmias: mechanisms and prevention

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12 December 2020

Electrophysiologic effects and clinical efficacy of oral propafenone therapy in patients with ventricular tachycardia

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12 December 2020

Triggered activity as a cause of bigeminy

1 reference

12 December 2020

On the mechanisms underlying digitalis toxicity in cardiac Purkinje fibers

1 reference

12 December 2020

10.1111/J.1476-5381.1988.TB11737.X

Identifiers

DOI

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19 October 2017

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19 October 2017

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