Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases (Q42224034)

18 October 2017

Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases (English)

1 reference

18 October 2017

1 reference

1 reference

6

1 reference

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2 June 2020

John D Martin

12

1 reference

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2 June 2020

Yuhui Huang

13

1 reference

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2 June 2020

21

Rakesh K Jain

1 reference

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2 June 2020

8

Keehoon Jung

1 reference

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2 June 2020

11

Takahiro Heishi

1 reference

2 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27733559%20AND%20SRC:MED&resulttype=core&format=json

22

Dai Fukumura

1 reference

2 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27733559%20AND%20SRC:MED&resulttype=core&format=json

3

Joao Incio

1 reference

2 June 2020

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16

Jurgen Weitz

1 reference

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2 June 2020

author name string

Nuh N Rahbari

1

1 reference

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2 June 2020

Dmitriy Kedrin

2

1 reference

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2 June 2020

Hao Liu

4

1 reference

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2 June 2020

William W Ho

5

1 reference

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2 June 2020

Christina M Edrich

7

1 reference

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2 June 2020

Julien Daubriac

9

1 reference

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2 June 2020

Ivy Chen

10

1 reference

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2 June 2020

Nir Maimon

14

1 reference

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2 June 2020

Christoph Reissfelder

15

1 reference

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2 June 2020

Yves Boucher

17

1 reference

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2 June 2020

Jeffrey W Clark

18

1 reference

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2 June 2020

Alan J Grodzinsky

19

1 reference

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2 June 2020

Dan G Duda

20

1 reference

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2 June 2020

language of work or name

English

0 references

publication date

1 October 2016

1 reference

Science Translational Medicine

18 October 2017

1 reference

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2 June 2020

volume

8

1 reference

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2 June 2020

issue

360

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2 June 2020

page(s)

360ra135

1 reference

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Myeloid Cells as Targets for Therapy in Solid Tumors

2 June 2020

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26 October 2017

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26 October 2017

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26 October 2017

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Tumor-associated hyaluronan limits efficacy of monoclonal antibody therapy

26 October 2017

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26 October 2017

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26 October 2017

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Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma.

26 October 2017

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Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice.

26 October 2017

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Therapeutic targeting of hyaluronan in the tumor stroma

26 October 2017

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26 October 2017

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Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

26 October 2017

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Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology

26 October 2017

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26 October 2017

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26 October 2017

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Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers

26 October 2017

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Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse

26 October 2017

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A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response

26 October 2017

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Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment.

26 October 2017

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Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy

26 October 2017

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Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

26 October 2017

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Bevacizumab-based therapies in the first-line treatment of metastatic colorectal cancer

26 October 2017

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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

26 October 2017

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

26 October 2017

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Accessories to the crime: functions of cells recruited to the tumor microenvironment

26 October 2017

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Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies.

26 October 2017

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Origins of tumor-associated macrophages and neutrophils.

26 October 2017

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Molecular pathways: hypoxia response in immune cells fighting or promoting cancer

26 October 2017

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Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look

26 October 2017

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Effect of sulfated glycosaminoglycans on tumor invasion and metastasis

26 October 2017

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Targeting hypoxia in cancer therapy

26 October 2017

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Molecular mechanisms and clinical applications of angiogenesis

26 October 2017

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Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors

26 October 2017

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Hyaluronan in human malignancies

26 October 2017

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Delivering nanomedicine to solid tumors

26 October 2017

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Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases

26 October 2017

1 reference

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Identification of splenic reservoir monocytes and their deployment to inflammatory sites

26 October 2017

1 reference

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Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo

26 October 2017

1 reference

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In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate.

26 October 2017

1 reference

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Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan

26 October 2017

1 reference

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Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver

26 October 2017

1 reference

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Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

26 October 2017

1 reference

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Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.

26 October 2017

1 reference

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Mouse colon carcinoma cells established for high incidence of experimental hepatic metastasis exhibit accelerated and anchorage-independent growth.

26 October 2017

1 reference

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Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF.

26 October 2017

1 reference

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Hyaluronan: from extracellular glue to pericellular cue.

26 October 2017

1 reference

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

26 October 2017

1 reference

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Elevated hyaluronan production induces mesenchymal and transformed properties in epithelial cells

26 October 2017

1 reference

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CD44 signaling through focal adhesion kinase and its anti-apoptotic effect

26 October 2017

1 reference

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Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway

26 October 2017

1 reference

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Roles of heparan-sulphate glycosaminoglycans in cancer

26 October 2017

1 reference

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Prognostic value of hyaluronan expression in non-small-cell lung cancer: Increased stromal expression indicates unfavorable outcome in patients with adenocarcinoma

26 October 2017

1 reference

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Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival

26 October 2017

1 reference

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Relationship between hyaluronan production and metastatic potential of mouse mammary carcinoma cells

26 October 2017

1 reference

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Overproduction of hyaluronan by expression of the hyaluronan synthase Has2 enhances anchorage-independent growth and tumorigenicity.

26 October 2017

1 reference

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Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion

26 October 2017

1 reference

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CD44v(3,8-10) is involved in cytoskeleton-mediated tumor cell migration and matrix metalloproteinase (MMP-9) association in metastatic breast cancer cells

26 October 2017

1 reference

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Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function

26 October 2017

1 reference

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Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity

26 October 2017

1 reference

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Transport of molecules in the tumor interstitium: a review

26 October 2017

1 reference

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

26 October 2017

1 reference

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Biosynthetic response of cartilage explants to dynamic compression

26 October 2017

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Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure

26 October 2017

1 reference

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Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models

29 May 2018

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The next frontier of molecular medicine: delivery of therapeutics.

29 May 2018

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Hyaluronan distribution in the normal epithelium of esophagus, stomach, and colon and their cancers

29 May 2018

1 reference

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A colon tumor model for anticancer agent evaluation

29 May 2018

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Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer.

29 May 2018

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High stromal hyaluronan level is associated with poor differentiation and metastasis in prostate cancer

17 August 2018

1 reference

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Hyaluronic acid/CD44H interaction induces cell detachment and stimulates migration and invasion of human glioma cells in vitro.

17 August 2018

1 reference

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Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors

17 August 2018

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Crossref

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Tumor cell-associated hyaluronan as an unfavorable prognostic factor in colorectal cancer

21 January 2018

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12 December 2020

Role of extracellular matrix assembly in interstitial transport in solid tumors

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12 December 2020

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid

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12 December 2020

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

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12 December 2020

Impact of bevacizumab on functional recovery and histology of the liver after resection of colorectal metastases

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12 December 2020

Angiotensin II Type 1a Receptor-deficient Mice with Hypotension and Hyperreninemia

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27733559%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27733559%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

27733559

1 reference