Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions (Q42201173)

18 October 2017

title

Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions (English)

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18 October 2017

Yunlong Ma

1

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18 October 2017

Wenji Yuan

2

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18 October 2017

Xianzhong Jiang

3

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18 October 2017

Wen-Yan Cui

4

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18 October 2017

Ming D Li

5

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18 October 2017

publication date

20 August 2014

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18 October 2017

published in

Molecular Neurobiology

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18 October 2017

volume

51

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18 October 2017

issue

1

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18 October 2017

page(s)

281-299

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Polygenic inheritance of Tourette syndrome, stuttering, attention deficit hyperactivity, conduct, and oppositional defiant disorder: the additive and subtractive effect of the three dopaminergic genes--DRD2, D beta H, and DAT1.

18 October 2017

cites work

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Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample

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12 December 2020

Association of dopamine receptor polymorphisms with schizophrenia and antipsychotic response in a South Indian population

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12 December 2020

Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations

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Alcohol consumption indices of genetic risk for alcohol dependence

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Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.

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The relationship between genetic influences on alcohol dependence and on patterns of alcohol consumption

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12 December 2020

The ANKK1 protein associated with addictions has nuclear and cytoplasmic localization and shows a differential response of Ala239Thr to apomorphine

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12 December 2020

Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers

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Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor

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12 December 2020

Genetics of dopamine receptors and drug addiction: a comprehensive review

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The genetic epidemiology of smoking

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12 December 2020

Brain dopamine and reward

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12 December 2020

Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African-American sample.

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12 December 2020

C957T polymorphism of the dopamine D2 receptor (DRD2) gene affects striatal DRD2 availability in vivo.

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12 December 2020

Accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine

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12 December 2020

Overexpression of dopamine D2 receptors reduces alcohol self-administration

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12 December 2020

Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients.

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12 December 2020

Binge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypes.

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12 December 2020

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12 December 2020

Influence of the dopamine D2 receptor (DRD2) genotype on neuroadaptive effects of alcohol and the clinical outcome of alcoholism

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12 December 2020

An association study of DRD2 gene polymorphisms with schizophrenia in a Chinese Han population.

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12 December 2020

Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse

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12 December 2020

Changes in extracellular dopamine induced by morphine and cocaine: crucial control by D2 receptors

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12 December 2020

Functional polymorphism of -141C Ins/Del in the dopamine D2 receptor gene promoter and schizophrenia

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12 December 2020

D2 receptors binding potential is not affected by Taq1 polymorphism at the D2 receptor gene

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12 December 2020

Lack of association between TaqI A1 allele of dopamine D2 receptor gene and alcohol-use disorders in atayal natives of Taiwan

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12 December 2020

The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans

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12 December 2020

A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence.

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12 December 2020

Psychiatric comorbidity of smoking and nicotine dependence

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12 December 2020

Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case–control and family samples

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12 December 2020

Association study of 45 candidate genes in nicotine dependence in Han Chinese.

1 reference

12 December 2020

No association between the dopamine d2 receptor taqi a1 allele and earlier age of onset of alcohol dependence according to different specified criteria

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12 December 2020

Dopamine receptors D1 and D2 are related to observed maternal behavior.

1 reference

12 December 2020

Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking

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12 December 2020

Dopamine D2 receptors and transporters in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography

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12 December 2020

Genetic markers of striatal dopamine predict individual differences in dysfunctional, but not functional impulsivity

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12 December 2020

Dopamine receptor D2 gene polymorphisms are associated in Taiwanese children with Tourette syndrome

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12 December 2020

Probabilities of alcohol high-risk drinking, abuse or dependence estimated on grounds of tobacco smoking and nicotine dependence

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12 December 2020

ANKK1/DRD2 locus variants are associated with rimonabant efficacy in aiding smoking cessation: pilot data

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12 December 2020

Association between the C957T polymorphism of the dopamine D2 receptor gene and schizophrenia

1 reference

12 December 2020

Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations

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12 December 2020

Allelic association of the D2 dopamine receptor gene with cocaine dependence

1 reference

12 December 2020

Estrogen differentially modulates nicotine-evoked dopamine release from the striatum of male and female rats

1 reference

12 December 2020

Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor

1 reference

12 December 2020

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

1 reference

12 December 2020

Association of short-term response to haloperidol treatment with a polymorphism in the dopamine D(2) receptor gene

1 reference

12 December 2020

Influence of DRD2 and ANKK1 genotypes on apomorphine-induced growth hormone (GH) response in alcohol-dependent patients

1 reference

12 December 2020

The genetics of smoking related behavior: a brief review

1 reference

12 December 2020

Dopamine D2 receptor (DRD2) gene and susceptibility to posttraumatic stress disorder: a study and replication

1 reference

12 December 2020

Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood

1 reference

12 December 2020

Nicotine addiction and comorbidity with alcohol abuse and mental illness

1 reference

12 December 2020

D2 dopamine receptor (DRD2) gene Taq1A polymorphism and the eating-related psychological traits in eating disorders (anorexia nervosa and bulimia) and obesity

1 reference

12 December 2020

Polymorphism of DRD2 gene and ADHD

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12 December 2020

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12 December 2020

DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability.

1 reference

12 December 2020

D2 dopamine receptor gene and cigarette smoking: a reward gene?

1 reference

12 December 2020

Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium.

1 reference

12 December 2020

The dopamine D2 receptor (DRD2) gene: a genetic risk factor in smoking.

1 reference

12 December 2020

Polymorphisms of the dopamine D2 receptor, serotonin transporter, and GABA(A) receptor beta(3) subunit genes and alcoholism in Mexican-Americans

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12 December 2020

Lack of effect of D2 dopamine receptor TaqI A polymorphism on smoking cessation

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12 December 2020

Association between the dopamine D2 receptor A2/A2 genotype and smoking behavior in the Japanese.

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12 December 2020

TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood

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12 December 2020

Behavioral mechanisms underlying the link between smoking and drinking.

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12 December 2020

Family-based association testing strongly implicates DRD2 as a risk gene for schizophrenia in Han Chinese from Taiwan.

1 reference

12 December 2020

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1 reference

12 December 2020

Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study

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12 December 2020

Association between the DRD2-141C Insertion/Deletion polymorphism and schizophrenia.

1 reference

12 December 2020

D2 receptor genetic variation and clinical response to antipsychotic drug treatment: a meta-analysis

1 reference

12 December 2020

Association study between the -141C Ins/Del and TaqI A polymorphisms of the dopamine D2 receptor gene and alcoholism

1 reference

12 December 2020

DRD2 haplotype associated with negative symptoms and sustained attention deficits in Han Chinese with schizophrenia in Taiwan

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12 December 2020

The interaction of reward genes with environmental factors in contribution to alcoholism in mexican americans

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12 December 2020

Association of dopamine receptor gene polymorphisms with the clinical course of Wilson disease

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12 December 2020

The 3' region of the DRD2 gene is involved in genetic susceptibility to schizophrenia

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12 December 2020

Lack of an allelic association between polymorphisms of the dopamine D2 receptor gene and alcohol dependence in the German population

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12 December 2020

Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving

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12 December 2020

DRD2 and PPP1R1B (DARPP-32) polymorphisms independently confer increased risk for autism spectrum disorders and additively predict affected status in male-only affected sib-pair families

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12 December 2020

Interaction between DRD2 C957T polymorphism and an acute psychosocial stressor on reward-related behavioral impulsivity.

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12 December 2020

Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients

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12 December 2020

Breaking barriers in the genomics and pharmacogenetics of drug addiction

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12 December 2020

What can the DRD2/alcoholism story teach us about association studies in psychiatric genetics?

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12 December 2020

Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk.

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12 December 2020

Dopaminergic system genes in childhood aggression: possible role for DRD2.

1 reference

12 December 2020

Association between smoking habits and dopamine receptor D2 taqI A A2 allele in Japanese males: a confirmatory study

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12 December 2020

Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new data

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12 December 2020

Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.

1 reference

12 December 2020

The dopamine D2 receptor 5'-flanking variant, -141C Ins/Del, is not associated with reduced dopamine D2 receptor density in vivo

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12 December 2020

C957T DRD2 polymorphism is associated with schizophrenia in Spanish patients

1 reference

12 December 2020

Polydrug dependence and psychiatric comorbidity among heroin injectors.

1 reference

12 December 2020

Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution

1 reference

12 December 2020

Sex differences in striatal dopamine release in healthy adults

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12 December 2020

The dopamine D2 receptor gene is a susceptibility locus for Parkinson's disease

1 reference

12 December 2020

Pharmacogenetics of responses to alcohol and genes that influence alcohol drinking

1 reference

12 December 2020

Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia

1 reference

12 December 2020

The A1 allele of the DRD2 gene (TaqI A polymorphisms) is associated with antisocial personality in a sample of alcohol-dependent patients

1 reference

12 December 2020

The genetics of alcoholism: identifying specific genes through family studies

1 reference

12 December 2020

Association and excess of transmission of a DRD2 haplotype in a sample of French schizophrenic patients

1 reference

12 December 2020

Dopaminergic genes predict individual differences in susceptibility to confirmation bias

1 reference

12 December 2020

No association between alcoholism and multiple polymorphisms at the dopamine D2 receptor gene (DRD2) in three distinct Taiwanese populations

1 reference

12 December 2020

Association analysis between dopamine receptor genes and bipolar affective disorder

1 reference

12 December 2020

Association between a polymorphism in the promoter region of the dopamine D2 receptor gene and schizophrenia in Japanese subjects: replication and evaluation for antipsychotic-related features.

1 reference

12 December 2020

Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.

1 reference

12 December 2020

Association in Japanese patients between neuroleptic malignant syndrome and functional polymorphisms of the dopamine D(2) receptor gene

1 reference

12 December 2020

D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele.

1 reference

12 December 2020

Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men.

1 reference

12 December 2020

Genetic triple dissociation reveals multiple roles for dopamine in reinforcement learning

1 reference

12 December 2020

DRD2 and ANKK1 genotype in alcohol-dependent patients with psychopathic traits: association and interaction study

1 reference

12 December 2020

Alcoholism and the D2 dopamine receptor gene

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12 December 2020

The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers

1 reference

12 December 2020

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

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12 December 2020

Associations of prenatal nicotine exposure and the dopamine related genes ANKK1 and DRD2 to verbal language.

1 reference

12 December 2020

A DRD2 and ANKK1 haplotype is associated with nicotine dependence.

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12 December 2020

Genetic and environmental contributions to smoking

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12 December 2020

Association of the D2 dopamine receptor A1 allele with alcoholism: Medical severity of alcoholism and type of controls

1 reference

12 December 2020

The D2 dopamine receptor gene variant C957T affects human fear conditioning and aversive priming

1 reference

12 December 2020

Common genetic vulnerability for nicotine and alcohol dependence in men

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12 December 2020

Allelic association analysis of the dopamine D2, D3, 5-HT2A, and GABA(A)gamma2 receptors and serotonin transporter genes with heroin abuse in Chinese subjects.

1 reference

12 December 2020

The taqI DRD2 A1 allele is associated with alcohol-dependence although its effect size is small

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12 December 2020

D2 dopamine receptor gene and alcoholism

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12 December 2020

Polymorphisms in dopamine receptors: what do they tell us?

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12 December 2020

Genetically determined differences in learning from errors

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12 December 2020

A large-scale meta-analysis of the association between the ANKK1/DRD2 Taq1A polymorphism and alcohol dependence

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12 December 2020

Dopamine D2 receptor gene (DRD2) haplotypes in Caucasians

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12 December 2020

Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans

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12 December 2020

A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins

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12 December 2020

Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism

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12 December 2020

Examining impulsivity as an endophenotype using a behavioral approach: a DRD2 TaqI A and DRD4 48-bp VNTR association study.

1 reference

12 December 2020

Environmental and genetic determinants of tobacco use: methodology for a multidisciplinary, longitudinal family-based investigation.

1 reference

12 December 2020

ANKK1, TTC12, and NCAM1 polymorphisms and heroin dependence: importance of considering drug exposure

1 reference

12 December 2020

Dopaminergic mutations: within-family association and linkage in multiplex alcohol dependence families

1 reference

12 December 2020

DRD2 genetic variation in relation to smoking and obesity in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

1 reference

12 December 2020

A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population

1 reference

12 December 2020

Evidence suggesting the role of specific genetic factors in cigarette smoking

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12 December 2020

The effects of the DRD2 polymorphism on smoking cessation and negative affect: evidence for a pharmacogenetic effect on mood

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12 December 2020

The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine.

1 reference

12 December 2020

Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction

1 reference

12 December 2020

DRD2 C957T and TaqIA Genotyping Reveals Gender Effects and Unique Low-Risk and High-Risk Genotypes in Alcohol Dependence

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12 December 2020

Genomewide Linkage Scan for Nicotine Dependence: Identification of a Chromosome 5 Risk Locus

1 reference

12 December 2020

The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects.

1 reference

12 December 2020

D2 Dopamine Receptor Gene (DRD2) Allele and Haplotype Frequencies in Alcohol Dependent and Control Subjects No Association with Phenotype or Severity of Phenotype

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12 December 2020

C957T polymorphism of the dopamine D2 receptor gene is associated with motor learning and heart rate.

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12 December 2020

Distinct functions of the two isoforms of dopamine D2 receptors

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12 December 2020

-141 C del/ins polymorphism of the dopamine receptor 2 gene is associated with schizophrenia in a British population.

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12 December 2020

Genetic predisposition in alcoholism: association of the D2 dopamine receptor TaqI B1 RFLP with severe alcoholics

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12 December 2020

No association between an allele at the D2 dopamine receptor gene (DRD2) and alcoholism.

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12 December 2020

No association between the dopamine D2 receptor gene and Korean alcoholism

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12 December 2020

Reward sensitivity and the D2 dopamine receptor gene: A case-control study of binge eating disorder

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12 December 2020

Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia.

1 reference

12 December 2020

Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias

1 reference

12 December 2020

Association between DRD2/ANKK1 Taq1A genotypes, depression and smoking cessation with nicotine replacement therapy

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12 December 2020

Association of DRD2 variants and Gilles de la Tourette syndrome in a family-based sample from a South American population isolate

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12 December 2020

Decreases in dopamine receptors but not in dopamine transporters in alcoholics

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12 December 2020

Concurrent validity of cocaine and sedative dependence diagnoses in opioid-dependent outpatients

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12 December 2020

A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia

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12 December 2020

Measures of current alcohol consumption and problems: two independent twin studies suggest a complex genetic architecture

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12 December 2020

The Dopamine D2 Receptor Locus as a Modifying Gene in Neuropsychiatric Disorders

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12 December 2020

The C/C genotype of the C957T polymorphism of the dopamine D2 receptor is associated with schizophrenia

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12 December 2020

Haplotypes at the DRD2 locus and severe alcoholism

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12 December 2020

Identification and characterization of two nuclear factor-kappaB sites in the regulatory region of the dopamine D2 receptor

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12 December 2020

Nerve growth factor regulates dopamine D(2) receptor expression in prolactinoma cell lines via p75(NGFR)-mediated activation of nuclear factor-kappaB.

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12 December 2020

D(2) dopamine receptor (DRD2) polymorphism is associated with severity of alcohol dependence

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12 December 2020

The genetic basis for smoking behavior: a systematic review and meta-analysis

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12 December 2020

Association between a promoter polymorphism in the dopamine D2 receptor gene and schizophrenia

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12 December 2020

Potential association of DRD2 and DAT1 genetic variation with heroin dependence

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12 December 2020

Genetic contributions to avoidance-based decisions: striatal D2 receptor polymorphisms

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12 December 2020

A possible smoking susceptibility locus on chromosome 11p12: evidence from sex-limitation linkage analyses in a sample of Australian twin families

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12 December 2020

Genetic correlations between smoking initiation and smoking behaviors in a twin sample

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12 December 2020

Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent

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12 December 2020

DRD2 promoter region variation predicts antipsychotic-induced weight gain in first episode schizophrenia

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12 December 2020

Smoking and drinking: a review of the literature

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12 December 2020

The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction

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12 December 2020

Genetic variation in three candidate genes and nicotine dependence, withdrawal and smoking cessation in hospitalized patients.

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12 December 2020

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

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12 December 2020

D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes

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12 December 2020

Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1

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12 December 2020

Genetic susceptibility to Parkinson's disease among South and North Indians: I. Role of polymorphisms in dopamine receptor and transporter genes and association of DRD4 120-bp duplication marker.

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12 December 2020

DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia

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12 December 2020

Rs1076560, a functional variant of the dopamine D2 receptor gene, confers risk of schizophrenia in Han Chinese

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12 December 2020

D2 dopamine receptor gene haplotypes and their influence on alcohol and tobacco consumption magnitude in alcohol-dependent individuals

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12 December 2020

Progress in searching for susceptibility loci and genes for smoking-related behaviour

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12 December 2020

Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence

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12 December 2020

Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence

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12 December 2020

DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking

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12 December 2020

Levels and correlates of polydrug use among heroin users and regular amphetamine users

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12 December 2020

Functional variation of the dopamine D2 receptor gene is associated with emotional control as well as brain activity and connectivity during emotion processing in humans

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12 December 2020

Association analysis of the dopamine receptor D2 (DRD2) SNP rs1076560 in alcoholic patients

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12 December 2020

New insights into the genetics of addiction

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12 December 2020

Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence

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12 December 2020

Functional analysis of the human D2 dopamine receptor missense variants

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12 December 2020

Psychopathology and HIV risk behaviors among injection drug users in and out of treatment

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12 December 2020

Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations.

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12 December 2020

Association of seven polymorphisms of the D2 dopamine receptor gene with brain receptor-binding characteristics

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12 December 2020

Association between dopaminergic genes (SLC6A3 and DRD2) and stuttering among Han Chinese.

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12 December 2020

C957T polymorphism of the human dopamine D2 receptor gene predicts extrastriatal dopamine receptor availability in vivo

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12 December 2020

Polymorphism of dopamine D2 and D4 receptor genes and Slavic-surnamed alcoholic patients

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12 December 2020

The association between DRD2/ANKK1 and genetically informed measures of alcohol use and problems

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12 December 2020

Allelic association of human dopamine D2 receptor gene in alcoholism

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12 December 2020

Menstrual cycle phase effects on nicotine withdrawal and cigarette craving: a review

1 reference

12 December 2020

Personality traits and dopamine receptors (D2 and D4): linkage studies in families of alcoholics

1 reference

12 December 2020

Meta-analysis of the association of the Taq1A polymorphism with the risk of alcohol dependency: a HuGE gene-disease association review

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12 December 2020

D2 dopamine receptor gene TaqI A1 and B1 restriction fragment length polymorphisms: enhanced frequencies in psychostimulant-preferring polysubstance abusers

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12 December 2020

Dopamine and drug addiction: the nucleus accumbens shell connection.

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12 December 2020

Gender differences in determinants of smoking initiation and persistence in California twins

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12 December 2020

DRD2 promoter region variation as a predictor of sustained response to antipsychotic medication in first-episode schizophrenia patients

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12 December 2020

Behavioral phenotypes of impulsivity related to the ANKK1 gene are independent of an acute stressor

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12 December 2020

10.1007/S12035-014-8826-2

Identifiers

DOI

1 reference

Dimensions Publication ID

18 October 2017

1040640492

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