Enhancing the rate of scaffold discovery with diversity-oriented prioritization (Q42183610)

18 October 2017

Enhancing the rate of scaffold discovery with diversity-oriented prioritization (English)

1 reference

18 October 2017

1 reference

3

Joshua A Bittker

1 reference

18 October 2017

S Joshua Swamidass

1

1 reference

18 October 2017

Bradley T Calhoun

series ordinal

2

1 reference

18 October 2017

Nicole E Bodycombe

series ordinal

4

1 reference

18 October 2017

Paul A Clemons

series ordinal

5

1 reference

18 October 2017

language of work or name

English

0 references

publication date

17 June 2011

1 reference

18 October 2017

1 reference

18 October 2017

27

1 reference

18 October 2017

16

1 reference

18 October 2017

2271-2278

1 reference

Compound set enrichment: a novel approach to analysis of primary HTS data

18 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Discovery of power-laws in chemical space.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

What do we know and when do we know it?

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Optimization of CAMD techniques 3. Virtual screening enrichment studies: a help or hindrance in tool selection?

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

ChemBank: a small-molecule screening and cheminformatics resource database

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Enrichment of high-throughput screening data with increasing levels of noise using support vector machines, recursive partitioning, and laplacian-modified naive bayesian classifiers

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Novel statistical approach for primary high-throughput screening hit selection

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Probing the primary screening efficiency by multiple replicate testing: a quantitative analysis of hit confirmation and false screening results of a biochemical assay

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Design and analysis of experiments with high throughput biological assay data.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Assessment of the consistency of medicinal chemists in reviewing sets of compounds.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Enrichment of extremely noisy high-throughput screening data using a naïve Bayes classifier

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Logistic regression and artificial neural network classification models: a methodology review

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

The properties of known drugs. 1. Molecular frameworks

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Enhancing the diversity of a corporate database using chemical database clustering and analysis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

An economic framework to prioritize confirmatory tests after a high-throughput screen.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Enhanced HTS hit selection via a local hit rate analysis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Detection and assignment of common scaffolds in project databases of lead molecules

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Managing bias in ROC curves.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

An efficient method for the detection and elimination of systematic error in high-throughput screening

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

The scaffold tree--visualization of the scaffold universe by hierarchical scaffold classification

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

The optimal discovery procedure for large-scale significance testing, with applications to comparative microarray experiments

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

Practical approaches to efficient screening: information-rich screening protocol.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150035

The minimum significant ratio: a statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21685049

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/BIOINFORMATICS/BTR369

1 reference

journals/bioinformatics/SwamidassCBBC11

18 October 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

18 October 2017

PubMed publication ID

21685049

1 reference