Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4. (Q42181842)

18 October 2017

Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4. (English)

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18 October 2017

1 reference

Martin Vaeth

2

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author name string

Katrien Pletinckx

1

1 reference

18 October 2017

Theresa Schneider

3

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18 October 2017

Niklas Beyersdorf

4

1 reference

18 October 2017

Thomas Hünig

5

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18 October 2017

Friederike Berberich-Siebelt

6

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18 October 2017

Manfred B Lutz

7

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18 October 2017

language of work or name

English

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publication date

2 December 2014

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European Journal of Immunology

18 October 2017

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18 October 2017

45

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18 October 2017

2

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18 October 2017

480-491

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https://api.crossref.org/works/10.1002%2FEJI.201444991

18 October 2017

1 reference

Transcriptional mechanisms underlying lymphocyte tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

CD28 and CTLA-4 coreceptor expression and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

The cyclin‐dependent kinase inhibitors p27Kip1 and p21Cip1 are not essential in T cell anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

CTLA-4 ligation blocks CD28-dependent T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Regulation of T-cell tolerance by calcium/NFAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Molecular mechanisms of CD4+ T-cell anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Fingerprints of anergic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Egr-2 and Egr-3 are negative regulators of T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Functional and molecular comparison of anergic and regulatory T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Immature and maturation-resistant human dendritic cells generated from bone marrow require two stimulations to induce T cell anergy in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Clonal anergy induced in mature V beta 6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Selective anergy of V beta 8+,CD4+ T cells in Staphylococcus enterotoxin B-primed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Antigenic strength controls the generation of antigen-specific IL-10-secreting T regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

NFAT, immunity and cancer: a transcription factor comes of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

NFAT transcription factors in control of peripheral T cell tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

An enigmatic tail of CD28 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

The contributions of T-cell anergy to peripheral T-cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Tolerance induction of human CD4+ T cells: markedly enhanced sensitivity of memory versus naive T cells to peripheral anergy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Activation and differentiation requirements of primary T cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Most lymphoid organ dendritic cell types are phenotypically and functionally immature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

CD28 facilitates the generation of Foxp3(-) cytokine responsive regulatory T cell precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Differentiation of effector CD4 T cell populations (*)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

An essential role of the transcription factor GATA-3 for the function of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

High TCR stimuli prevent induced regulatory T cell differentiation in a NF-κB-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Persistent antigenic stimulation alters the transcription program in T cells, resulting in antigen-specific tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Protection from graft-versus-host disease with a novel B7 binding site-specific mouse anti-mouse CD28 monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

CTLA4 ligation attenuates AP-1, NFAT and NF-kappaB activity in activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

T-cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II I–E

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

Naive T cells are resistant to anergy induction by anti-CD3 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

inferred from DOI database lookup

7 January 2021

based on heuristic

Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

inferred from DOI database lookup

7 January 2021

based on heuristic

Culture of bone marrow cells in GM-CSF plus high doses of lipopolysaccharide generates exclusively immature dendritic cells which induce alloantigen-specific CD4 T cell anergy in vitro

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444991

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/EJI.201444991

1 reference

18 October 2017

1 reference