Metallothionein 1+2 protect the CNS during neuroglial degeneration induced by 6-aminonicotinamide (Q42163275)

17 October 2017

Metallothionein 1+2 protect the CNS during neuroglial degeneration induced by 6-aminonicotinamide (English)

1 reference

17 October 2017

4

1 reference

17 October 2017

1

Milena Penkowa

0 references

Mercedes Giralt

series ordinal

2

object named as

Mercedes Giralt

1 reference

17 October 2017

Jordi Camats

3

1 reference

PubMed ID

11835189

17 October 2017

language of work or name

English

0 references

publication date

1 March 2002

1 reference

The Journal of Comparative Neurology

17 October 2017

1 reference

17 October 2017

444

1 reference

17 October 2017

2

1 reference

17 October 2017

174-189

1 reference

Structural and functional impact of the transgenic expression of cytokines in the CNS.

17 October 2017

1 reference

Localization of metallothionein-I and -III expression in the CNS of transgenic mice with astrocyte-targeted expression of interleukin 6.

21 January 2018

1 reference

Metallothionein (MT)-III: generation of polyclonal antibodies, comparison with MT-I+II in the freeze lesioned rat brain and in a bioassay with astrocytes, and analysis of Alzheimer's disease brains.

21 January 2018

1 reference

Enhanced seizures and hippocampal neurodegeneration following kainic acid-induced seizures in metallothionein-I + II-deficient mice

21 January 2018

1 reference

Local delivery of TNF by retrovirus-transduced T lymphocytes exacerbates experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Analysis of the effects of overexpression of metallothionein-I in transgenic mice on the reproductive toxicology of cadmium

21 January 2018

1 reference

Molecular profile of reactive astrocytes--implications for their role in neurologic disease

21 January 2018

1 reference

Antioxidants, oxidative stress, and degenerative neurological disorders

21 January 2018

1 reference

Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice.

21 January 2018

1 reference

Effect of 6-aminonicotinamide on metabolism of astrocytes and C6-glioma cells.

21 January 2018

1 reference

Inhibition of NADPH supply by 6-aminonicotinamide: effect on glutathione, nitric oxide and superoxide in J774 cells

21 January 2018

1 reference

Antioxidant and antiapoptotic function of metallothioneins in HL-60 cells challenged with copper nitrilotriacetate.

21 January 2018

1 reference

In vitro and in vivo studies on the degradation of metallothionein

21 January 2018

1 reference

Involvement of differential metallothionein expression in free radical sensitivity of RTG-2 and CHSE-214 cells

21 January 2018

1 reference

Spongiform neuropathy induced in dogs by prolonged, low-level administration of 6-aminonicotinamide (6-ANA).

21 January 2018

1 reference

Experimental gliopathy in the adult rat CNS: effect on the blood-spinal cord barrier.

21 January 2018

1 reference

Metallothioneins and cell death by anticancer drugs

21 January 2018

1 reference

Enhanced sensitivity to oxidative stress in cultured embryonic cells from transgenic mice deficient in metallothionein I and II genes

21 January 2018

1 reference

The protein thiol metallothionein as an antioxidant and protectant against antineoplastic drugs.

21 January 2018

1 reference

Myelin basic protein content of aggregating rat brain cell cultures treated with cytokines and/or demyelinating antibody: effects of macrophage enrichment

21 January 2018

1 reference

Extracellular metallothionein effects on lymphocyte activities

21 January 2018

1 reference

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium

21 January 2018

1 reference

Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide

21 January 2018

1 reference

Effect of nitric oxide synthesis inhibition on mouse liver and brain metallothionein expression.

21 January 2018

1 reference

Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice

21 January 2018

1 reference

RETRACTED: Metallothionein I+II expression and their role in experimental autoimmune encephalomyelitis

21 January 2018

1 reference

IL-6 deficiency leads to reduced metallothionein-I+II expression and increased oxidative stress in the brain stem after 6-aminonicotinamide treatment

21 January 2018

1 reference

Increased astrocytic expression of metallothioneins I + II in brainstem of adult rats treated with 6-aminonicotinamide.

21 January 2018

1 reference

Impaired inflammatory response to glial cell death in genetically metallothionein-I- and -II-deficient mice.

21 January 2018

1 reference

Zinc or copper deficiency-induced impaired inflammatory response to brain trauma may be caused by the concomitant metallothionein changes

21 January 2018

1 reference

Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide

21 January 2018

1 reference

Astrocyte cultures from transgenic mice to study the role of metallothionein in cytotoxicity of tert-butyl hydroperoxide

21 January 2018

1 reference

Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase

21 January 2018

1 reference

6-Aminonicotinamide inhibition of the pentose phosphate pathway in rat neocortex

21 January 2018

1 reference

Evidence for a protective role of metallothionein-1 in focal cerebral ischemia

21 January 2018

1 reference

Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation

21 January 2018

1 reference

Immune regulation within the central nervous system.

21 January 2018

1 reference

Depletion of systemic macrophages by liposome-encapsulated clodronate attenuates striatal macrophage invasion and neurodegeneration following local endotoxin infusion in gerbils

21 January 2018

1 reference

Metallothionein Treatment Reduces Proinflammatory Cytokines IL-6 and TNF-α and Apoptotic Cell Death during Experimental Autoimmune Encephalomyelitis (EAE)

21 January 2018

1 reference

Interactions of metallothionein with murine lymphocytes: plasma membrane binding and proliferation

21 January 2018

1 reference

7 January 2021

Metallothionein protects DNA from copper-induced but not iron-induced cleavage in vitro

1 reference

7 January 2021

Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage

1 reference

7 January 2021

Transgenic mice and cytokine actions in the brain: bridging the gap between structural and functional neuropathology

1 reference

7 January 2021

An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration

1 reference

7 January 2021

Identification of metallothionein receptors in human astrocytes

1 reference

7 January 2021

Detection of circulating metallothionein in rats injected with zinc or cadmium

1 reference

7 January 2021

Development of a competitive double antibody radioimmunoassay for rat metallothionein

1 reference

7 January 2021

Regulation of the isoforms of metallothionein

1 reference

7 January 2021

Age-dependent susceptibility of CNS glial populations in situ to the antimetabolite 6-aminonicotinamide

1 reference

7 January 2021

Immunomodulatory activities of extracellular metallothionein. I. Metallothionein effects on antibody production

1 reference

7 January 2021

Effects of gamma radiation on levels of brain metallothionein and lipid peroxidation in transgenic mice.

1 reference

7 January 2021

Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice

1 reference

7 January 2021

Altered Central Nervous System Cytokine-Growth Factor Expression Profiles and Angiogenesis in Metallothionein-I+II Deficient Mice

1 reference

7 January 2021

Impaired inflammatory response and increased oxidative stress and neurodegeneration after brain injury in interleukin-6-deficient mice

1 reference

7 January 2021

Oxidative stress and neurodegenerative disorders

1 reference

7 January 2021

Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals

1 reference

7 January 2021

Immunomodulatory activities of extracellular metallothionein. II. Effects on macrophage functions

1 reference

7 January 2021

Identifiers

DOI

10.1002/CNE.10149

1 reference

17 October 2017

1 reference

PubMed ID

11835189