Human skin dendritic cells can be targeted in situ by intradermal injection of antibodies against lectin receptors. (Q42106951)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25346475%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Human skin dendritic cells can be targeted in situ by intradermal injection of antibodies against lectin receptors (English)

1 reference

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21 February 2020

1 reference

1

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21 February 2020

Christoph H Tripp

3

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21 February 2020

Nikolaus Romani

9

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21 February 2020

author name string

Sandra Schaffenrath

2

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21 February 2020

Daniela Reider

4

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21 February 2020

Kerstin Komenda

5

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21 February 2020

Barbara Del Frari

6

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21 February 2020

Gabriel Djedovic

7

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21 February 2020

Susanne Ebner

8

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21 February 2020

publication date

1 December 2014

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21 February 2020

published in

Experimental Dermatology

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21 February 2020

volume

23

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21 February 2020

issue

12

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21 February 2020

page(s)

909-915

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Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance

21 February 2020

cites work

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29 May 2018

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29 May 2018

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29 May 2018

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Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells

29 May 2018

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Targeting Dendritic Cells in vivo for Cancer Therapy

29 May 2018

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Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

29 May 2018

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29 May 2018

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Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses

29 May 2018

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Decisions about dendritic cells: past, present, and future

29 May 2018

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Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

29 May 2018

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Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses

29 May 2018

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Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

29 May 2018

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Targeting skin dendritic cells to improve intradermal vaccination.

29 May 2018

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Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC.

29 May 2018

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Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR

29 May 2018

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The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells

29 May 2018

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Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens.

29 May 2018

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Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

29 May 2018

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29 May 2018

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Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.

29 May 2018

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Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis.

29 May 2018

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29 May 2018

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Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells

29 May 2018

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Resident and "inflammatory" dendritic cells in human skin

29 May 2018

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Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses.

29 May 2018

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The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

29 May 2018

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Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting

29 May 2018

1 reference

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Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice

29 May 2018

1 reference

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Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

29 May 2018

1 reference

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

29 May 2018

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The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments

29 May 2018

1 reference

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Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules

29 May 2018

1 reference

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Migration and maturation of Langerhans cells in skin transplants and explants

29 May 2018

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Induction of antigen-specific immunity with a vaccine targeting NY-ESO-1 to the dendritic cell receptor DEC-205.

29 May 2018

1 reference

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Trial watch: Dendritic cell-based interventions for cancer therapy

17 August 2018

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Intradermal delivery of TLR agonists in a human explant skin model: preferential activation of migratory dendritic cells by polyribosinic-polyribocytidylic acid and peptidoglycans.

17 August 2018

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CD70-CD27 interaction augments CD8+ T-cell activation by human epidermal Langerhans cells.

17 August 2018

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Poly(I:C)-Treated human langerhans cells promote the differentiation of CD4+ T cells producing IFN-gamma and IL-10.

17 August 2018

1 reference

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Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells

17 August 2018

1 reference

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Expression of C-type lectin receptors by subsets of dendritic cells in human skin.

17 August 2018

1 reference

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CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to granulocyte-macrophage colony-stimulating factor plus tumor necrosis factor alpha: II. Functional analysis

17 August 2018

1 reference

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Anatomical distribution analysis reveals lack of Langerin+ dermal dendritic cells in footpads and tail of C57BL/6 mice

3 November 2018

1 reference

12 December 2020

Mature Human Langerhans Cells Derived from CD34+ Hematopoietic Progenitors Stimulate Greater Cytolytic T Lymphocyte Activity in the Absence of Bioactive IL-12p70, by Either Single Peptide Presentation or Cross-Priming, Than Do Dermal-Interstitial or

1 reference

12 December 2020

Inhibition of melanoma growth by targeting of antigen to dendritic cells via an anti-DEC-205 single-chain fragment variable molecule

1 reference

12 December 2020

Preferential induction of CD4+ T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1

1 reference

12 December 2020

Migration of langerhans cells and dermal dendritic cells in skin organ cultures: augmentation by TNF-alpha and IL-1beta

1 reference

12 December 2020

Cutting edge: langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo

1 reference

12 December 2020

Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation

1 reference

12 December 2020

Isolation of skin dendritic cells from mouse and man

1 reference

12 December 2020

Identifiers

DOI

10.1111/EXD.12573

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25346475%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25346475%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25346475%20AND%20SRC:MED&resulttype=core&format=json