Histone deacetylase inhibitors enhance expression of NKG2D ligands in Ewing sarcoma and sensitize for natural killer cell-mediated cytolysis (Q42106350)

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English	Histone deacetylase inhibitors enhance expression of NKG2D ligands in Ewing sarcoma and sensitize for natural killer cell-mediated cytolysis	scientific article

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scholarly article

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Europe PubMed Central

16 October 2017

Histone deacetylase inhibitors enhance expression of NKG2D ligands in Ewing sarcoma and sensitize for natural killer cell-mediated cytolysis (English)

1 reference

Europe PubMed Central

16 October 2017

R Maarten Egeler

7

object named as

R Maarten Egeler

1 reference

Europe PubMed Central

16 October 2017

Arjan Lankester

9

object named as

Arjan C Lankester

1 reference

Europe PubMed Central

16 October 2017

Marco W Schilham

2

object named as

Marco W Schilham

1 reference

Europe PubMed Central

16 October 2017

Dagmar Berghuis

1

object named as

Dagmar Berghuis

1 reference

Europe PubMed Central

16 October 2017

4

object named as

Susy J Santos

1 reference

Europe PubMed Central

16 October 2017

author name string

Hanneke I Vos

3

1 reference

Europe PubMed Central

16 October 2017

Stephan Kloess

5

1 reference

Europe PubMed Central

16 October 2017

Emilie P Buddingh'

6

1 reference

Europe PubMed Central

16 October 2017

Pancras Cw Hogendoorn

8

1 reference

Europe PubMed Central

16 October 2017

publication date

8 February 2012

1 reference

Europe PubMed Central

16 October 2017

Clinical Sarcoma Research

1 reference

Europe PubMed Central

16 October 2017

2

1 reference

Europe PubMed Central

16 October 2017

1

1 reference

Europe PubMed Central

16 October 2017

8

1 reference

Europe PubMed Central

16 October 2017

https://scigraph.springernature.com/pub.10.1186/2045-3329-2-8

0 references

A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells.

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29 May 2018

Killing the killer: natural killer cells to treat Ewing's sarcoma

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29 May 2018

Cytotoxicity of activated natural killer cells against pediatric solid tumors

1 reference

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29 May 2018

Effect of NKG2D ligand expression on host immune responses

1 reference

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29 May 2018

Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group

1 reference

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Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

1 reference

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The role of interferons in the treatment of osteosarcoma

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Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort

1 reference

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29 May 2018

Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKCalpha phosphorylation

1 reference

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The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

1 reference

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The NFATc2 gene is involved in a novel cloned translocation in a Ewing sarcoma variant that couples its function in immunology to oncology

1 reference

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29 May 2018

Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition

1 reference

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29 May 2018

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

1 reference

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29 May 2018

Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351702

29 May 2018

NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways

1 reference

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29 May 2018

Soluble NKG2D ligands: prevalence, release, and functional impact.

1 reference

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29 May 2018

EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma

1 reference

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29 May 2018

Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy

1 reference

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29 May 2018

Interleukin-15 improves cytotoxicity of natural killer cells via up-regulating NKG2D and cytotoxic effector molecule expression as well as STAT1 and ERK1/2 phosphorylation

1 reference

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Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group

1 reference

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Sarcomas: genetics, signalling, and cellular origins. Part 1: The fellowship of TET.

1 reference

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Histone deacetylase inhibitors induce cell death and enhance the apoptosis-inducing activity of TRAIL in Ewing's sarcoma cells

1 reference

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Prospects for the use of NK cells in immunotherapy of human cancer.

1 reference

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29 May 2018

Expression of cellular FLICE inhibitory protein, caspase-8, and protease inhibitor-9 in Ewing sarcoma and implications for susceptibility to cytotoxic pathways.

1 reference

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Safety assessment of intensive induction with vincristine, ifosfamide, doxorubicin, and etoposide (VIDE) in the treatment of Ewing tumors in the EURO-E.W.I.N.G. 99 clinical trial

1 reference

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Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B.

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Natural killer cell-based immunotherapeutic strategies

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The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

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Antitumor effects of histone deacetylase inhibitor on Ewing's family tumors

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PI3K/AKT is involved in mediating survival signals that rescue Ewing tumour cells from fibroblast growth factor 2-induced cell death

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Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer

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Downregulation and/or release of NKG2D ligands as immune evasion strategy of human neuroblastoma

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MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors

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Ewing's sarcoma: ex vivo sensitivity towards natural and lymphokine-activated killing

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification of histopathologic changes following chemotherapy in Ewing's sarcoma of bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/22587892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

StatBite: FDA oncology drug product approvals in 2009

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https://pubmed.ncbi.nlm.nih.gov/22587892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/2045-3329-2-8

1 reference

Europe PubMed Central

16 October 2017

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1 reference

Europe PubMed Central

16 October 2017

1 reference

Europe PubMed Central

16 October 2017

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