Targeted disruption of the heat shock protein 20-phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy. (Q42094222)

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scientific article published on 28 October 2014

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English	Targeted disruption of the heat shock protein 20-phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy.	scientific article published on 28 October 2014

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23 February 2020

Targeted disruption of the heat shock protein 20-phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy (English)

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23 February 2020

Christina L. Elliott

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23 February 2020

Maria P Hortigon-Vinagre

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23 February 2020

Tamara Martin Gimenez

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Tamara P Martin

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23 February 2020

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Jane E Findlay

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28 October 2014

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23 February 2020

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23 February 2020

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23 February 2020

923-927

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Compartmentalisation of second messenger signalling pathways

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PKA phosphorylation of the small heat-shock protein Hsp20 enhances its cardioprotective effects

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Small heat shock protein 20 interacts with protein phosphatase-1 and enhances sarcoplasmic reticulum calcium cycling

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Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes

1 reference

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Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases.

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Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts

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Transducible recombinant small heat shock-related protein, HSP20, inhibits vasospasm and platelet aggregation

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17 August 2018

Inducible cAMP early repressor (ICER) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to beta-adrenergic receptor stimulation.

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Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1

1 reference

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12 December 2020

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10.1016/J.FOB.2014.10.011

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23 February 2020

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23 February 2020

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23 February 2020

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