Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance. (Q42091667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24870561%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance (English)

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19 March 2020

4

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19 March 2020

Nathalie Janel

5

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19 March 2020

Raphael Scharfmann

8

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19 March 2020

author name string

Latif Rachdi

1

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19 March 2020

Dulanjalee Kariyawasam

2

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19 March 2020

Virginie Aïello

3

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19 March 2020

Jean-Maurice Delabar

6

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19 March 2020

Michel Polak

7

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19 March 2020

publication date

28 May 2014

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19 March 2020

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19 March 2020

volume

13

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19 March 2020

issue

14

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19 March 2020

page(s)

2221-2229

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describes a project that uses

19 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4111677/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Pdx1 maintains β cell identity and function by repressing an α cell program

1 reference

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Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.

29 May 2018

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Incretin action in the pancreas: potential promise, possible perils, and pathological pitfalls

29 May 2018

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Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome.

29 May 2018

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Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111677

Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals

29 May 2018

1 reference

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Diabetes mellitus and the β cell: the last ten years

29 May 2018

1 reference

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DYRK1A: a master regulatory protein controlling brain growth.

29 May 2018

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L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway

29 May 2018

1 reference

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Context-specific α- to-β-cell reprogramming by forced Pdx1 expression.

29 May 2018

1 reference

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MNB/DYRK1A as a multiple regulator of neuronal development

29 May 2018

1 reference

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Distinctive Phenotypic Abnormalities Associated with Submicroscopic 21q22 Deletion Including DYRK1A.

29 May 2018

1 reference

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Transgenic overexpression of active calcineurin in beta-cells results in decreased beta-cell mass and hyperglycemia

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111677

Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111677

Disruption of Tsc2 in pancreatic beta cells induces beta cell mass expansion and improved glucose tolerance in a TORC1-dependent manner.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111677

Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111677

Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111677

Increased islet apoptosis in Pdx1+/- mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111677

Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111677

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

29 May 2018

1 reference

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The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint

29 May 2018

1 reference

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Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer.

29 May 2018

1 reference

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On the origin of pancreatic endocrine cells

29 May 2018

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The stunned beta cell: a brief history

29 May 2018

1 reference

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Pancreatic beta-cell mass in European subjects with type 2 diabetes

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Role for VPAC2 receptor-mediated signals in pancreas development

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Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24870561

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.29250

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24870561%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24870561%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference