Reversible phosphorylation at the C-terminal regulatory domain of p21(Waf1/Cip1) modulates proliferating cell nuclear antigen binding (Q42055057)

15 October 2017

Reversible phosphorylation at the C-terminal regulatory domain of p21(Waf1/Cip1) modulates proliferating cell nuclear antigen binding (English)

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15 October 2017

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Scott MT

1

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15 October 2017

Morrice N

series ordinal

2

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15 October 2017

Ball KL

series ordinal

3

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15 October 2017

language of work or name

English

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publication date

1 April 2000

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Journal of Biological Chemistry

15 October 2017

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15 October 2017

275

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15 October 2017

11529-11537

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15 October 2017

15

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D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

15 October 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Analysis of wild-type and mutant p21WAF-1 gene activities

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Inhibition of cyclin-dependent kinases by p21

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1)

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Activity and nature of p21(WAF1) complexes during the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

New functional activities for the p21 family of CDK inhibitors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

p21-containing cyclin kinases exist in both active and inactive states

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Cyclin-dependent kinase inhibitor p21 modulates the DNA primer-template recognition complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Resistance of human nucleotide excision repair synthesis in vitro to p21Cdn1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Activation of human cyclin-dependent kinases in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Probing protein structure using biochemical and biophysical methods. Proteolysis, matrix-assisted laser desorption/ionization mass spectrometry, high-performance liquid chromatography and size-exclusion chromatography of p21Waf1/Cip1/Sdi1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

p21: structure and functions associated with cyclin-CDK binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Ectopic p21(WAF1) expression induces differentiation-specific cell cycle changes in PC12 cells characteristic of nerve growth factor treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Human and plant proliferating-cell nuclear antigen have a highly conserved binding site for the p53-inducible gene product p21WAF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

p53-Dependent growth arrest and altered p53-immunoreactivity following metabolic labelling with 32P ortho-phosphate in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Antisense blockade of p21/WAF1 decreases radiation-induced G2 arrest in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

Dephosphorylation of p53 at Ser20 after cellular exposure to low levels of non-ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11529

21 January 2018

Identifiers

DOI

10.1074/JBC.275.15.11529

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15 October 2017

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