Add-on aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan (Q41998504)

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scientific article published on 22 May 2012

Language	Label	Description	Also known as
English	Add-on aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan	scientific article published on 22 May 2012

Statements

scholarly article

1 reference

Europe PubMed Central

15 October 2017

Add-on aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan (English)

1 reference

Europe PubMed Central

15 October 2017

Hiroyuki Kobori

6

1 reference

Europe PubMed Central

15 October 2017

author name string

Bai Lei

1

1 reference

Europe PubMed Central

15 October 2017

Daisuke Nakano

2

1 reference

Europe PubMed Central

15 October 2017

Yu-Yan Fan

3

1 reference

Europe PubMed Central

15 October 2017

Kento Kitada

4

1 reference

Europe PubMed Central

15 October 2017

Hirofumi Hitomi

5

1 reference

Europe PubMed Central

15 October 2017

Hirohito Mori

7

1 reference

Europe PubMed Central

15 October 2017

Tsutomu Masaki

8

1 reference

Europe PubMed Central

15 October 2017

Akira Nishiyama

9

1 reference

Europe PubMed Central

15 October 2017

publication date

22 May 2012

1 reference

Europe PubMed Central

15 October 2017

Journal of Pharmacological Sciences

1 reference

Europe PubMed Central

15 October 2017

119

1 reference

Europe PubMed Central

15 October 2017

2

1 reference

Europe PubMed Central

15 October 2017

131-138

1 reference

Europe PubMed Central

15 October 2017

Short-Term Calorie Restriction in Early Life Attenuates the Development of Proteinuria but Not Glucose Intolerance in Type 2 Diabetic OLETF Rats.

1 reference

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Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice

1 reference

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Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability

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Chronic kidney disease growth factors in renal fibrosis

1 reference

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Effects of mineralocorticoid receptor blockade on glucocorticoid-induced renal injury in adrenalectomized rats

1 reference

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The proximal tubule in the pathophysiology of the diabetic kidney

1 reference

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Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats

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Cubilin is essential for albumin reabsorption in the renal proximal tubule

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Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockade

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Microalbuminuria as a risk factor: the influence of renin-angiotensin system blockade

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A high-powered view of the filtration barrier

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Recent advances in tissue (pro)renin imaging

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Maintenance of glomerular filtration barrier integrity requires laminin alpha5.

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Strict angiotensin blockade prevents the augmentation of intrarenal angiotensin II and podocyte abnormalities in type 2 diabetic rats with microalbuminuria.

1 reference

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5 June 2018

The collecting duct is the major source of prorenin in diabetes

1 reference

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5 June 2018

Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats

1 reference

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The serial cultivation of human diploid cell strains

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Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin-converting enzyme inhibition

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Pharmacokinetics of valsartan in patients with liver disease

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Effect of ACE inhibition on glomerular permselectivity and tubular albumin concentration in the renal ablation model.

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Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney.

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18 August 2018

A reduction of unilateral ureteral obstruction-induced renal fibrosis by a therapy combining valsartan with aliskiren.

1 reference

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18 August 2018

Inhibition of the renal renin-angiotensin system and renoprotection by pitavastatin in type1 diabetes

1 reference

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18 August 2018

Direct renin inhibition improved insulin resistance and adipose tissue dysfunction in type 2 diabetic KK-A(y) mice

1 reference

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Treatment of db/db diabetic mice with triptolide: a novel therapy for diabetic nephropathy

1 reference

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18 August 2018

Pharmacokinetics and bioequivalence study of three oral formulations of valsartan 160 mg: a single-dose, randomized, open-label, three-period crossover comparison in healthy Indian male volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396743

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Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396743

18 August 2018

Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats.

1 reference

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Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy

1 reference

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Aliskiren combined with losartan in type 2 diabetes and nephropathy

1 reference

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Albuminuria response to very high-dose valsartan in type 2 diabetes mellitus.

1 reference

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Enhanced effect of combined treatment with SMP-534 (antifibrotic agent) and losartan in diabetic nephropathy

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Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria

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Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption

1 reference

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Losartan ameliorates progression of glomerular structural changes in diabetic KKAy mice

1 reference

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Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.

1 reference

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Effects of combined ACE inhibitor and angiotensin II antagonist treatment in human chronic nephropathies

1 reference

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Baseline characteristics in the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE)

1 reference

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Olmesartan for the Delay or Prevention of Microalbuminuria in Type 2 Diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396743

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Absorption, Distribution, Metabolism, and Elimination of the Direct Renin Inhibitor Aliskiren in Healthy Volunteers

1 reference

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Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: the BENEDICT-B randomized trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/22673148

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan

1 reference

https://pubmed.ncbi.nlm.nih.gov/22673148

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aliskiren reduces albuminuria and oxidative stress, and elevates glomerular filtration rates in Japanese patients with advanced diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22673148

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormonal and hemodynamic effects of aliskiren and valsartan and their combination in sodium-replete normotensive individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/22673148

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular cell adhesion molecule-1 expression in the renal interstitium of diabetic KKAy mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22673148

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22673148

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1254/JPHS.12031FP

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

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