A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells (Q41992926)

14 October 2017

A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells (English)

1 reference

human embryonic stem cell

14 October 2017

0 references

1 reference

Danwei Huangfu

5

0 references

Federico González

object named as

Federico González

3

0 references

author name string

Zengrong Zhu

1

1 reference

PMCID

4471821

14 October 2017

Nipun Verma

2

1 reference

PMCID

4471821

14 October 2017

Zhong-Dong Shi

4

1 reference

14 October 2017

28 May 2015

1 reference

14 October 2017

1 reference

14 October 2017

4

1 reference

14 October 2017

6

1 reference

14 October 2017

1103-1111

1 reference

Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

The iCRISPR platform for rapid genome editing in human pluripotent stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

CRISPR-Cas9 knockin mice for genome editing and cancer modeling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

A guide to genome engineering with programmable nucleases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Efficient designer nuclease-based homologous recombination enables direct PCR screening for footprintless targeted human pluripotent stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

DNA targeting specificity of RNA-guided Cas9 nucleases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Human pluripotent stem cells: an emerging model in developmental biology.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

RNA-guided human genome engineering via Cas9

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Multiplex genome engineering using CRISPR/Cas systems

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

A TALEN genome-editing system for generating human stem cell-based disease models

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Transposon-mediated BAC transgenesis in human ES cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Genetic engineering of human pluripotent cells using TALE nucleases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Off-target assessment of CRISPR-Cas9 guiding RNAs in human iPS and mouse ES cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471821

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26028531

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEMCR.2015.04.016

1 reference

14 October 2017

1 reference

14 October 2017

1 reference

PMCID

4471821