Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance (Q41991754)

http://europepmc.org/abstract/PMC/5700341

8 January 2018

title

Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance (English)

1 reference

http://europepmc.org/abstract/PMC/5700341

8 January 2018

main subject

Mycobacterium tuberculosis

1 reference

1 reference

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26

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Claudio U Köser

29

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Diana Machado

4

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Danesh Moradigaravand

7

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João Perdigão

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Isabel Portugal

10

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1 June 2020

Thomas A Kohl

14

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1 June 2020

Taane G Clark

16

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Htin Lin Aung

21

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Julian Parkhill

23

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25

Soumya Swaminathan

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1 June 2020

5

Sönke Andres

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1 June 2020

8

Francesc Coll

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3

Matthias Merker

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12

Dina Nair

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27

Stefan Niemann

1 reference

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1 June 2020

19

Roland Diel

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1 June 2020

author name string

Yoshio Nakatani

1

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1 June 2020

Helen K Opel-Reading

2

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1 June 2020

S Siva Kumar

6

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1 June 2020

Thomas Schön

11

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1 June 2020

K R Uma Devi

13

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1 June 2020

Patrick Beckert

15

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1 June 2020

Gugu Maphalala

17

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1 June 2020

Derrick Khumalo

18

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Kadri Klaos

20

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1 June 2020

Gregory M Cook

22

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1 June 2020

Kurt L Krause

28

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Sharon J Peacock

24

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1 June 2020

language of work or name

English

0 references

publication date

2 October 2017

1 reference

http://europepmc.org/abstract/PMC/5700341

8 January 2018

published in

Antimicrobial Agents and Chemotherapy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28971867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

61

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1 June 2020

issue

12

1 reference

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Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives.

1 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Sensititre MycoTB plate compared to Bactec MGIT 960 for first- and second-line antituberculosis drug susceptibility testing in Tanzania: a call to operationalize MICs

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteria

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Whole-genome sequencing for rapid susceptibility testing of M. tuberculosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Importance of the genetic diversity within the Mycobacterium tuberculosis complex for the development of novel antibiotics and diagnostic tests of drug resistance

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Challenging a dogma: antimicrobial susceptibility testing breakpoints for Mycobacterium tuberculosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

The alanine racemase of Mycobacterium smegmatis is essential for growth in the absence of D-alanine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

A Side Reaction of Alanine Racemase: Transamination of Cycloserine,

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Characterization of the alanine racemases from two mycobacteria

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Assessment of Metabolic Changes in Mycobacterium smegmatis Wild-Type and alr Mutant Strains: Evidence of a New Pathway of d-Alanine Biosynthesis.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

N(2)-substituted D,L-cycloserine derivatives: synthesis and evaluation as alanine racemase inhibitors

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5700341

Alanine racemase mutants of Mycobacterium tuberculosis require D-alanine for growth and are defective for survival in macrophages and mice

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28971867

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.01575-17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28971867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28971867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

28971867

1 reference